The continuously increasing cost of the US healthcare system has received significant
attention. Central to the ideas aimed at curbing this trend is the use of technology in the form …

Background The design of computerized systems able to support automated detection of
threatening conditions in critically ill patients such as systemic inflammatory response …

Objectives: To specify when delays of specific 3-hour bundle Surviving Sepsis Campaign
guideline recommendations applied to severe sepsis or septic shock become harmful and …

There is a large body of evidence showing that delayed initiation of sepsis bundle is
associated with adverse clinical outcomes in patients with sepsis. However, it is …

OBJECTIVES: Earlier treatment of sepsis leads to decreased mortality. Epic is an electronic
medical record providing a predictive alert system for sepsis, the Epic Sepsis Model (ESM) …

Background The diagnosis and management of sepsis remain a global health care
challenge. Digital technologies have the potential to improve sepsis care. Objective The aim …

Purpose To evaluate the effectiveness of a multidisciplinary, hospital-wide program as part
of an electronic sepsis alert tool. Materials and methods We used data from 15 hospitals …

Objective Surveillance algorithms that predict patient decompensation are increasingly
integrated with clinical workflows to help identify patients at risk of in-hospital deterioration …

Objective The study sought to determine the impact of a digital sepsis alert on patient
outcomes in a UK multisite hospital network. Materials and Methods A natural experiment …

We developed a novel computer program, the Intelligent Sepsis Management System,
based on Sepsis-3 definitions and 2016 Surviving Sepsis Campaign guidelines and …