Determinants of obesity in Latin America

SRG Ferreira, Y Macotela, LA Velloso, MA Mori - Nature metabolism, 2024 - nature.com
Obesity rates are increasing almost everywhere in the world, although the pace and timing
for this increase differ when populations from developed and develo** countries are …

Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity

M Pigeyre, FT Yazdi, Y Kaur, D Meyre - Clinical science, 2016 - portlandpress.com
In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Luteolin protects against high fat diet-induced cognitive deficits in obesity mice

Y Liu, X Fu, N Lan, S Li, J Zhang, S Wang, C Li… - Behavioural brain …, 2014 - Elsevier
The epidemic and experimental studies have confirmed that the obesity can lead to
neuroinflammation, neurodegenerative diseases and adversely affect cognition. Despite the …

Gene-nutrient interactions and susceptibility to human obesity

JJ Castillo, RA Orlando, WS Garver - Genes & nutrition, 2017 - Springer
A large number of genome-wide association studies, transferability studies, and candidate
gene studies performed in diverse populations around the world have identified gene …

ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

LJ Baier, YL Muller, MS Remedi, M Traurig… - Diabetes, 2015 - diabetesjournals.org
Missense variants in KCNJ11 and ABCC8, which encode the KIR6. 2 and SUR1 subunits of
the β-cell KATP channel, have previously been implicated in type 2 diabetes, neonatal …

The Microbiota and Evolution of Obesity

MJA Saad, A Santos - Endocrine Reviews, 2024 - academic.oup.com
Obesity is a major global concern and is generally attributed to a combination of genetic and
environmental factors. Several hypotheses have been proposed to explain the evolutionary …

[HTML][HTML] Differential proteomic analysis to identify potential biomarkers associated with quality traits of Dezhou donkey meat using a data-independent acquisition (DIA …

W Chai, J Xu, H Qu, Q Ma, M Zhu, M Li, Y Zhan… - Lwt, 2022 - Elsevier
Donkey meat has been recognized as a nutritive food for human consumption in China
because of its protein, vitamins, and mineral contents. However, the genetic mechanisms …

Functional toxicogenomic assessment of triclosan in human HepG2 cells using genome-wide CRISPR-Cas9 screening

P **
J **ao, M Cai, X Yu, X Hu, G Chen, X Wan… - The American Journal of …, 2022 - cell.com
Over the past two decades, genome-wide association studies (GWASs) have successfully
advanced our understanding of the genetic basis of complex traits. Despite the fruitful …