Alcohol is a potent somnogen and one of the most commonly used “over the counter” sleep
aids. In healthy non-alcoholics, acute alcohol decreases sleep latency, consolidates and …

The past decade has brought many advances in our understanding of GABA A receptor-
mediated ethanol action in the central nervous system. We now know that specific GABA A …

Alcohol intake remains controlled in a majority of users but becomes “compulsive,” ie,
continues despite adverse consequences, in a minority who develop alcohol addiction …

Alcohol acts on numerous cellular and molecular targets to regulate neuronal
communication within the brain. Chronic alcohol exposure and acute withdrawal generate …

Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in
synaptic function are prominent among these effects. Acute exposure to EtOH activates or …

Rationale An increasingly compelling literature points to a major role for the glutamate
system in mediating the effects of alcohol on behavior and the pathophysiology of …

Context Alcohol facilitates γ-aminobutyric acid (GABA) function, and GABA type A (GABA A)
receptor–facilitating agents suppress alcohol withdrawal symptoms. Advances in molecular …

Since 1996, nearly 100 genes have been studied for their effects related to ethanol in mice
using genetic modifications including gene deletion, gene overexpression, gene knock‐in …

We previously showed that apremilast, an FDA-approved PDE4 inhibitor, selectively alters
behavioral responses to ethanol and certain GABAergic drugs in a PKA-dependent manner …

Alcoholic neuropathy : Current Opinion in Neurology Alcoholic neuropathy : Current Opinion in
Neurology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …