The emergence of antibiotic resistance drives an essential race against time to reveal new
molecular structures capable of addressing this alarming global health problem. Snake …

Venom components are invaluable in biomedical research owing to their specificity and
potency. Many of these components exist in two genera of rattlesnakes, Crotalus and …

Phospholipase A 2 toxins present in snake venoms interact with biological membranes and
serve as structural models for the design of small peptides with anticancer, antibacterial and …

The membrane-active nature of phospholipase A2-derived peptides makes them potential
candidates for antineoplastic and antibacterial therapies. Two short 13-mer C-terminal …

Snake venoms are rich and intriguing sources of biologically-active molecules that act on
target cells, modulating a diversity of physiological functions and presenting promising …

The specificity and potency of venom components give them a unique advantage in
develo** various pharmaceutical drugs. Though venom is a cocktail of proteins, rarely are …

Background: Research involving snake venom has gradually surpassed the simple
discovery of new molecules using purification and structural characterization processes, and …

Bothrops asper and Bothrops atrox are important venomous snakes from Ecuador
responsible for the most of ophidic accidents, which in the past were treated with a national …

Secreted phospholipases A2 are snake-venom proteins with many biological activities,
notably anti-tumor activity. Phospholipases from the same snake type but different …

High molecular weight proteins are present abundantly in viperid venoms. The amino acid
sequence can be highly variable, contributing to the structure and function diversity of snake …