Water models for biomolecular simulations

AV Onufriev, S Izadi - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Modern simulation and modeling approaches to investigation of biomolecular structure and
function rely heavily on a variety of methods—water models—to approximate the influence …

Progress in the prediction of pKa values in proteins

E Alexov, EL Mehler, N Baker… - Proteins: structure …, 2011 - Wiley Online Library
The pKa‐cooperative aims to provide a forum for experimental and theoretical researchers
interested in protein pKa values and protein electrostatics in general. The first round of the …

A simplified and accurate model of power-performance efficiency on emergent GPU architectures

S Song, C Su, B Rountree… - 2013 IEEE 27th …, 2013 - ieeexplore.ieee.org
Emergent heterogeneous systems must be optimized for both power and performance at
exascale. Massive parallelism combined with complex memory hierarchies form a barrier to …

Understanding GPU power: A survey of profiling, modeling, and simulation methods

RA Bridges, N Imam, TM Mintz - ACM Computing Surveys (CSUR), 2016 - dl.acm.org
Modern graphics processing units (GPUs) have complex architectures that admit
exceptional performance and energy efficiency for high-throughput applications. Although …

General purpose water model can improve atomistic simulations of intrinsically disordered proteins

PS Shabane, S Izadi, AV Onufriev - Journal of chemical theory …, 2019 - ACS Publications
Unconstrained atomistic simulations of intrinsically disordered proteins and peptides (IDP)
remain a challenge: widely used,“general purpose” water models tend to favor overly …

Why double-stranded RNA resists condensation

IS Tolokh, SA Pabit, AM Katz, Y Chen… - Nucleic acids …, 2014 - academic.oup.com
The addition of small amounts of multivalent cations to solutions containing double-stranded
DNA leads to inter-DNA attraction and eventual condensation. Surprisingly, the …

Heterogeneous task scheduling for accelerated openmp

TRW Scogland, B Rountree, W Feng… - 2012 IEEE 26th …, 2012 - ieeexplore.ieee.org
Heterogeneous systems with CPUs and computational accelerators such as GPUs, FPGAs
or the upcoming Intel MIC are becoming mainstream. In these systems, peak performance …

A fast and robust Poisson–Boltzmann solver based on adaptive Cartesian grids

AH Boschitsch, MO Fenley - Journal of chemical theory and …, 2011 - ACS Publications
An adaptive Cartesian grid (ACG) concept is presented for the fast and robust numerical
solution of the 3D Poisson–Boltzmann equation (PBE) governing the electrostatic …