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Host and viral zinc-finger proteins in COVID-19
S Esposito, G D'Abrosca, A Antolak… - International journal of …, 2022 - mdpi.com
An unprecedented effort to tackle the ongoing COVID-19 pandemic has characterized the
activity of the global scientific community over the last two years. Hundreds of published …
activity of the global scientific community over the last two years. Hundreds of published …
Targeting allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to identify natural product inhibitors via structure-based computational …
Cancer has been viewed as one of the deadliest diseases worldwide. Among various types
of cancer, breast cancer is the most common type of cancer in women …
of cancer, breast cancer is the most common type of cancer in women …
Structural differences in 3C-like protease (Mpro) from SARS-CoV and SARS-CoV-2: molecular insights revealed by molecular dynamics simulations
Novel coronavirus SARS-CoV-2 has infected millions of people with thousands of mortalities
globally. The main protease (Mpro) is vital in processing replicase polyproteins. Both the …
globally. The main protease (Mpro) is vital in processing replicase polyproteins. Both the …
[HTML][HTML] Identifying COVID-19 severity-related SARS-CoV-2 mutation using a machine learning method
SARS-CoV-2 shows great evolutionary capacity through a high frequency of genomic
variation during transmission. Evolved SARS-CoV-2 often demonstrates resistance to …
variation during transmission. Evolved SARS-CoV-2 often demonstrates resistance to …
Genomic characterization of SARS‐CoV‐2 isolates from patients in Turkey reveals the presence of novel mutations in spike and nsp12 proteins
E Sahin, G Bozdayi, S Yigit, H Muftah… - Journal of medical …, 2021 - Wiley Online Library
Novel mutations have been emerging in the genome of severe acute respiratory syndrome‐
coronavirus 2 (SARS‐CoV‐2); consequently, the evolving of more virulent and treatment …
coronavirus 2 (SARS‐CoV‐2); consequently, the evolving of more virulent and treatment …
[HTML][HTML] Role of SARS-CoV-2 mutations in the evolution of the COVID-19 pandemic
Summary Objectives The SARS-CoV-2 pandemic and large-scale genomic surveillance
provided an exceptional opportunity to analyze mutations that appeared over three years in …
provided an exceptional opportunity to analyze mutations that appeared over three years in …
Genetic diversity and evolutionary dynamics of the Omicron variant of SARS-CoV-2 in Morocco
Among the numerous variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) that have been reported worldwide, the emergence of the Omicron variant has …
CoV-2) that have been reported worldwide, the emergence of the Omicron variant has …
Defective ORF8 dimerization in SARS-CoV-2 delta variant leads to a better adaptive immune response due to abrogation of ORF8-MHC1 interaction
In India, during the second wave of the COVID-19 pandemic, the breakthrough infections
were mainly caused by the SARS-COV-2 delta variant (B. 1.617. 2). It was reported that …
were mainly caused by the SARS-COV-2 delta variant (B. 1.617. 2). It was reported that …
E156G and Arg158, Phe-157/del mutation in NTD of spike protein in B. 1.617. 2 lineage of SARS-CoV-2 leads to immune evasion through antibody escape
Emerging variants of SARS-CoV-2 with better immune escape mechanisms and higher
transmissibility remains a persistent threat across the globe. B. 1.617. 2 (Delta) variant was …
transmissibility remains a persistent threat across the globe. B. 1.617. 2 (Delta) variant was …
[HTML][HTML] Evaluation of immune evasion in SARS-CoV-2 Delta and Omicron variants
Emerging SARS-CoV-2 variants with higher transmissibility and immune escape remain a
persistent threat across the globe. This is evident from the recent outbreaks of the Delta (B …
persistent threat across the globe. This is evident from the recent outbreaks of the Delta (B …