Considerable advances made in defining the aetiology, pathogenesis, and pathology of
Parkinson's disease (PD) have resulted in the development and rapid expansion of the …

There is consensus that amelioration of the motor symptoms of Parkinson's disease is most
effective with l-DOPA (levodopa). However, this necessary therapeutic step is biased by an …

Orally administered levodopa remains the most effective symptomatic treatment for
Parkinson's disease (PD). The introduction of levodopa therapy is often delayed, however …

Whether a drug such as levodopa, which is prescribed for long periods, may be toxic is a
legitimate and even indispensable question. The problem is no different from that posed by …

We determined systemic oxidative stress in Parkinson's disease (PD) patients, patients with
other neurological diseases (OND) and healthy controls by measurement of in vitro …

Dieses Buch vermittelt einen kompetenten und fächerübergreifenden Überblick über das
aktuelle Wissen auf dem Gebiet der Parkinson-Krankheit. Es ist im deutschsprachigen …

Many in vitro studies have shown that levodopa is a potent toxin which is lethal to various
cultured neuronal and non‐neuronal cells. The in vitro toxicity of levodopa is linked mainly to …

Idiopathic Parkinson's disease (PD) is the most common neurodegenerative disorder. An
important step in diagnosing the dis-ease has been achieved with the development of the …

Parkinson's disease (PD) is a chronic and progressive neurological disorder characterized
by selective degeneration of dopaminergic neurons (DAergic) in the substantia nigra pars …

Neuroinflammation is a main component of Parkinson's disease (PD) neuropathology,
where unremitting reactive microglia and microglia-secreted soluble molecules such as …