Understanding the interplay of multiple components (steric, electrostatic, stereoelectronic,
dispersive, etc.) that define the overall energy, structure, and reactivity of organic molecules …

Although carbon is the central element of organic chemistry, oxygen is the central element of
stereoelectronic control in organic chemistry. Generally, a molecule with a C–O bond has …

Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …

Nitroxide-mediated polymerization (NMP) is a controlled/living radical polymerization
(CLRP) technique that enables the design of well-defined, functional and complex …

Abstract Methanol‐to‐olefin (MTO) catalysis is a very active field of research because there
is a wide variety of sometimes conflicting mechanistic proposals. An example is the ongoing …

Organic chemists tend to consider the conformation of compounds as a consequence of
repulsive steric interactions. In other words,“the steric effect” means “repulsive” in many …

The combination of structural diversity at several levels and limited chemical shift dispersion
ensures that NMR spectra of carbohydrates are relatively difficult to interpret. This …

Organofluorine compounds are widely used in many different applications, ranging from
pharmaceuticals and agrochemicals to advanced materials and polymers. It has been …

Transforming the fluorine gauche effect from an academic curiosity into a powerful acyclic
conformational control strategy has enriched molecular design. This expansive approach to …

This review outlines the ubiquitous nature of hyperconjugative interactions and their role in
the structure and reactivity of organic molecules. After defining the common …