Nanoformulations-based metronomic chemotherapy: mechanism, challenges, recent advances, and future perspectives

VK Panthi, K Dua, SK Singh, G Gupta, PM Hansbro… - Pharmaceutics, 2023 - mdpi.com
Cancer-related death is a significant health and economic burden worldwide, and some
conventional chemotherapy is associated with limited effectiveness in completely curing …

Metronomic chemotherapy and drug repurposing: A paradigm shift in oncology

N Jan, S Sofi, H Qayoom, A Shabir, BU Haq, MA Macha… - Heliyon, 2024 - cell.com
Cancer represents a significant global health and economic burden due to its high mortality
rates. While effective in some instances, traditional chemotherapy often falls short of entirely …

Machine learning for quantitative finance applications: A survey

F Rundo, F Trenta, AL Di Stallo, S Battiato - Applied Sciences, 2019 - mdpi.com
Featured Application The described approaches can be used in various applications in the
field of quantitative finance from HFT trading systems to financial portfolio allocation and …

Deep LSTM with reinforcement learning layer for financial trend prediction in FX high frequency trading systems

F Rundo - Applied Sciences, 2019 - mdpi.com
High-frequency trading is a method of intervention on the financial markets that uses
sophisticated software tools, and sometimes also hardware, with which to implement high …

Ad-hoc shallow neural network to learn hyper filtered photoplethysmographic (ppg) signal for efficient car-driver drowsiness monitoring

F Rundo, C Spampinato, S Conoci - Electronics, 2019 - mdpi.com
In next-generation cars, safety equipment related to assisted driving systems commonly
known as ADAS (advanced driver-assistance systems) are of particular interest for the major …

Advanced deep learning embedded motion radiomics pipeline for predicting anti-PD-1/PD-L1 immunotherapy response in the treatment of bladder cancer: preliminary …

F Rundo, C Spampinato, GL Banna, S Conoci - Electronics, 2019 - mdpi.com
A key objective of modern medicine is precision medicine, whose purpose is to personalize
the treatment based on the specific characteristics of the patients and their illness. To guide …

Metronomic chemotherapy in non‑small cell lung cancer

Y Shu, S Weng, S Zheng - Oncology Letters, 2020 - spandidos-publications.com
Metronomic chemotherapy (MCT) is defined as the rhythmic chemotherapy of low‑dose
cytotoxic drugs with short or no drug‑free breaks over prolonged periods. MCT affects tumor …

Phytochemicals intended for anticancer effects at preclinical levels to clinical practice: Assessment of formulations at nanoscale for non-small cell lung cancer (NSCLC …

THP Nguyen, VB Kumar, VK Ponnusamy, TTT Mai… - Process …, 2021 - Elsevier
Over the past few decades, many of the phytochemicals have been shown to possess
extraordinary anticancer effects, clinical tested, approved as drugs, and currently in use. A …

Metronomic oral vinorelbine for the treatment of advanced non-small cell lung cancer: a multicenter international retrospective analysis

A Camerini, GL Banna, S Cinieri, A Pezzuto… - Clinical and …, 2019 - Springer
Purpose Metronomic oral vinorelbine (MOV) could be a treatment option for unfit patients
with advanced non-small cell lung cancer (NSCLC) based on its safety profile and high …

Immune Checkpoint Inhibitors in “Special” NSCLC Populations: A Viable Approach?

G Bronte, DM Cosi, C Magri, A Frassoldati… - International Journal of …, 2023 - mdpi.com
Over the last decade, the therapeutic scenario for advanced non-small-cell lung cancer
(NSCLC) has undergone a major paradigm shift. Immune checkpoint inhibitors (ICIs) have …