Peroxisome proliferator-activated receptors (PPARs) are fatty acid-activated transcription
factors of nuclear hormone receptor superfamily that regulate energy metabolism. Currently …

The proliferator-activated receptor γ (PPARγ), a member of the nuclear receptor superfamily,
is one of the most extensively studied ligand-inducible transcription factors. Since its …

The ability of mammals to resist body fat accumulation is linked to their ability to expand the
number and activity of “brown adipocytes” within white fat depots. Activation of β-adrenergic …

Cells are constantly exposed to a large variety of lipids. Traditionally, these molecules were
thought to serve as simple energy storing molecules. More recently it has been realized that …

The peroxisome proliferator activated receptors (PPARs) are nuclear receptors that play key
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …

The nuclear receptor Rev-erbα regulates circadian rhythm and metabolism, but its effects
are modest and it has been considered to be a secondary regulator of the cell-autonomous …

The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is a key regulator
of adipocyte differentiation in vivo and ex vivo and has been shown to control the expression …

The peroxisome proliferator-activated receptor α (PPARα, or NR1C1) is a nuclear hormone
receptor activated by a structurally diverse array of synthetic chemicals known as …

Adipogenesis is tightly controlled by a complex network of transcription factors acting at
different stages of differentiation. Peroxisome proliferator‐activated receptor γ (PPARγ) and …

Peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein
α (C/EBPα) are key activators of adipogenesis. They mutually induce the expression of each …