Streptavidin-saporin: Converting biotinylated materials into targeted toxins
LR Ancheta, PA Shramm, R Bouajram, D Higgins… - Toxins, 2023 - mdpi.com
Streptavidin-Saporin can be considered a type of 'secondary'targeted toxin. The scientific
community has taken advantage of this conjugate in clever and fruitful ways using many …
community has taken advantage of this conjugate in clever and fruitful ways using many …
Dbh+ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart
T Sun, A Grassam-Rowe, Z Pu, Y Li, H Ren… - Nature …, 2023 - nature.com
The heterogeneity of functional cardiomyocytes arises during heart development, which is
essential to the complex and highly coordinated cardiac physiological function. Yet the …
essential to the complex and highly coordinated cardiac physiological function. Yet the …
Innovation and disruptive science determine the future of cardiothoracic surgery
F Beyersdorf - European Journal of Cardio-Thoracic Surgery, 2024 - academic.oup.com
One of the currently most asked questions in the field of medicine is how any specialty in the
future will evolve to ensure better health for the patients by using current, unparalleled …
future will evolve to ensure better health for the patients by using current, unparalleled …
High-resolution atlas of the develo** human heart and the great vessels
The human heart and adjoining great vessels consist of multiple cell types vital for life, yet
many remain uncharacterised molecularly during development. Here, we performed a high …
many remain uncharacterised molecularly during development. Here, we performed a high …
Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes
The sinoatrial node regulates the heart rate throughout life. Failure of this primary
pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the …
pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the …
Probabilistic learning of the Purkinje network from the electrocardiogram
The identification of the Purkinje conduction system in the heart is a challenging task, yet
essential for a correct definition of cardiac digital twins for precision cardiology. Here, we …
essential for a correct definition of cardiac digital twins for precision cardiology. Here, we …
Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pum** of peripheral collecting lymphatic vessels in mice
Lymphatic muscle cells (LMCs) within the wall of collecting lymphatic vessels exhibit tonic
and autonomous phasic contractions, which drive active lymph transport to maintain tissue …
and autonomous phasic contractions, which drive active lymph transport to maintain tissue …
Transcriptional regulation of the postnatal cardiac conduction system heterogeneity
Y Oh, R Abid, S Dababneh, M Bakr, T Aslani… - Nature …, 2024 - nature.com
The cardiac conduction system (CCS) is a network of specialized cardiomyocytes that
coordinates electrical impulse generation and propagation for synchronized heart …
coordinates electrical impulse generation and propagation for synchronized heart …
Lymphatic muscle cells are unique cells that undergo aging induced changes
Lymphatic muscle cells (LMCs) within the wall of collecting lymphatic vessels exhibit tonic
and autonomous phasic contractions, which drive active lymph transport to maintain tissue …
and autonomous phasic contractions, which drive active lymph transport to maintain tissue …
Role of Genetic Variation in Transcriptional Regulatory Elements in Heart Rhythm
Genetic predisposition to cardiac arrhythmias has been a field of intense investigation.
Research initially focused on rare hereditary arrhythmias, but over the last two decades, the …
Research initially focused on rare hereditary arrhythmias, but over the last two decades, the …