An atlas of CNV maps in cattle, goat and sheep

Y Huang, Y Li, X Wang, J Yu, Y Cai, Z Zheng… - Science China Life …, 2021 - Springer
Copy number variation (CNV) is the most prevalent type of genetic structural variation that
has been recognized as an important source of phenotypic variation in humans, animals …

Next-generation development and application of codon model in evolution

MK Gupta, R Vadde - Frontiers in genetics, 2023 - frontiersin.org
To date, numerous nucleotide, amino acid, and codon substitution models have been
developed to estimate the evolutionary history of any sequence/organism in a more …

Deciphering the role of FOXP4 in long COVID: exploring genetic associations, evolutionary conservation, and drug identification through bioinformatics analysis

MK Gupta, G Gouda, R Vadde - Functional & Integrative Genomics, 2024 - Springer
Long COVID (LC) refers to a condition characterized by a variety of lingering symptoms that
persist for more than 4 to 12 weeks following the initial acute SARS-CoV-2 infection. Recent …

[HTML][HTML] Characterization of haplotypes and single nucleotide polymorphisms associated with Gn1a for high grain number formation in rice plant

G Gouda, MK Gupta, R Donde, J Kumar, M Parida… - Genomics, 2020 - Elsevier
Rice serves as one of the essential staple food for half of the global human population.
However, due to rapid human population growth, there is an increase in food demand …

[HTML][HTML] Prevalence of CFTR variants in primary immunodeficiency patients with bronchiectasis is an important modifying cofactor

D Lawless, HL Allen, JED Thaventhiran… - Journal of Allergy and …, 2023 - Elsevier
Background Cystic fibrosis (CF) is one of the most common life-limiting autosomal-recessive
disorders and is caused by genetic defects in the CF transmembrane conductance regulator …

A computational structural biology study to understand the impact of mutation on structure–function relationship of inward-rectifier potassium ion channel Kir6. 2 in …

MK Gupta, R Vadde - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D) is clinically characterized via hyperglycemia. Polymorphism
rs5219 in the KCNJ11 gene is a risk factor for develo** T2D in humans. KCNJ11 encodes …

Is adipose tissue an immunological organ?

R Vadde, MK Gupta… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Recently, several studies have reported endocrine properties in adipose tissues. The
adipose tissue has also been reported to be associated with thermal insulation, mechanical …

Unique footprints of balancing selection in bovine genome

SS Nayak, M Panigrahi, D Rajawat, K Jain, A Sharma… - 3 Biotech, 2024 - Springer
Balancing selection is the process of selection that preserves various alleles within a
population. Studying the areas undergoing balancing selection is essential, because it …

Complete Mitochondrial Genomes of Four Pelodiscus sinensis Strains and Comparison with Other Trionychidae Species

J Chen, J Jiao, X Yuan, X Huang, L Huang, L Lin… - Biology, 2023 - mdpi.com
Simple Summary The Chinese soft-shelled turtle (Pelodiscus sinensis) is an economically
important aquatic reptile species with rich nutrition and medicinal value. However, the wild …

Functional foods in the prevention of colorectal cancer

S Bonala, MK Gupta, R Vadde - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Colorectal cancer (CRC) ranks second for incidence in females (third in males). Currently, a
broad spectrum of treatment options exists for the treatment of colorectal tumors. However …