Serial femtosecond crystallography: A revolution in structural biology

JM Martin-Garcia, CE Conrad, J Coe… - Archives of biochemistry …, 2016 - Elsevier
Macromolecular crystallography at synchrotron sources has proven to be the most influential
method within structural biology, producing thousands of structures since its inception. While …

[HTML][HTML] Hybrid CMOS detectors for high-speed X-ray imaging

JL Porter, Q Looker, L Claus - Review of Scientific Instruments, 2023 - pubs.aip.org
Hybrid CMOS (hCMOS) x-ray framing cameras are a new and powerful detector option for
experiments in the fields of Inertial Confinement Fusion (ICF) and High Energy Density …

[PDF][PDF] Processing serial crystallography data with CrystFEL: a step-by-step guide

TA White - Acta Crystallographica Section D: Structural Biology, 2019 - journals.iucr.org
This article provides a step-by-step guide to the use of the CrystFEL software for processing
serial crystallography data from an X-ray free-electron laser or a synchrotron light source …

[PDF][PDF] X-ray detectors at the Linac Coherent Light Source

G Blaj, P Caragiulo, G Carini, S Carron… - Journal of …, 2015 - journals.iucr.org
Free-electron lasers (FELs) present new challenges for camera development compared with
conventional light sources. At SLAC a variety of technologies are being used to match the …

Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams

K Nass, L Foucar, TRM Barends… - Journal of …, 2015 - journals.iucr.org
Proteins that contain metal cofactors are expected to be highly radiation sensitive since the
degree of X-ray absorption correlates with the presence of high-atomic-number elements …

The CSPAD megapixel x-ray camera at LCLS

P Hart, S Boutet, G Carini, M Dubrovin… - X-Ray free-electron …, 2012 - spiedigitallibrary.org
The Linear Coherent Light Source (LCLS), a free electron laser operating from 250eV
to10keV at 120Hz, is opening windows on new science in biology, chemistry, and solid …

[PDF][PDF] New Python-based methods for data processing

NK Sauter, J Hattne… - … Section D: Biological …, 2013 - journals.iucr.org
Current pixel-array detectors produce diffraction images at extreme data rates (of up to 2 TB
h− 1) that make severe demands on computational resources. New multiprocessing …

[PDF][PDF] The ePix10k 2-megapixel hard X-ray detector at LCLS

TB Van Driel, S Nelson, R Armenta, G Blaj… - Journal of …, 2020 - journals.iucr.org
The ePix10ka2M (ePix10k) is a new large area detector specifically developed for X-ray free-
electron laser (XFEL) applications. The hybrid pixel detector was developed at SLAC to …

[HTML][HTML] Discerning best practices in XFEL-based biological crystallography–standards for nonstandard experiments

A Gorel, I Schlichting, TRM Barends - IUCrJ, 2021 - scripts.iucr.org
Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) is a novel
tool in structural biology. In contrast to conventional crystallography, SFX relies on merging …

Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser

KR Beyerlein, HO Jönsson… - Proceedings of the …, 2018 - National Acad Sciences
The bright ultrafast pulses of X-ray Free-Electron Lasers allow investigation into the structure
of matter under extreme conditions. We have used single pulses to ionize and probe water …