Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021‏ - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Ultrasound-responsive droplets for therapy: A review

H Lea-Banks, MA O'reilly, K Hynynen - Journal of Controlled Release, 2019‏ - Elsevier
The last two decades have seen the development of acoustically activated droplets, also
known as phase-change emulsions, from a diagnostic tool to a therapeutic agent. Through …

[HTML][HTML] Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions

M Aliabouzar, OD Kripfgans, JB Fowlkes… - … für Medizinische Physik, 2023‏ - Elsevier
The development of phase-shift droplets has broadened the scope of ultrasound-based
biomedical applications. When subjected to sufficient acoustic pressures, the …

[HTML][HTML] Impact of perfluoropentane microdroplets diameter and concentration on acoustic droplet vaporization transition efficiency and oxygen scavenging

RP Benton, N Al Rifai, K Stone, A Clark, B Zhang… - Pharmaceutics, 2022‏ - mdpi.com
Acoustic droplet vaporization is the ultrasound-mediated phase change of liquid droplets
into gas microbubbles. Following the phase change, oxygen diffuses from the surrounding …

Perfluorocarbon microdroplets stabilized by cellulose nanofibers: Toward ultrasound-mediated diagnostics and therapy

K Loskutova - 2023‏ - diva-portal.org
Ultrasound contrast agents consist of gas-filled micrometer-sized bubbles that are injected
into the blood stream. Ultrasound contrast agents are an invaluable tool for ultrasound …

Investigation of the mechanisms of oxygen delivery and cell death in oxygen-enhanced sonodynamic therapy

A Vasilyeva - 2022‏ - ora.ox.ac.uk
Sonodynamic therapy, which is usually defined as ultrasound-mediated activation of certain
drugs, is of substantial interest in the field of oncology. However, currently there is no …

Therapeutic Ultrasound: Improved Image Guidance and Combinatorial Treatments for Recurrent Prostate Cancer

GJ Anthony - 2019‏ - search.proquest.com
Cases of radio-recurrent prostate cancer (PCa) are difficult to treat effectively and would
benefit from the advancement of non-invasive, image-guided alternative therapies …