Lifestyle interventions for the prevention and treatment of hypertension

PL Valenzuela, P Carrera-Bastos, BG Gálvez… - Nature Reviews …, 2021 - nature.com
Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

The role of adipokines in inflammatory mechanisms of obesity

TV Kirichenko, YV Markina, AI Bogatyreva… - International Journal of …, 2022 - mdpi.com
Adipokines are currently widely studied cellular signaling proteins produced by adipose
tissue and involved in various processes, including inflammation; energy and appetite …

The role of resistin as a regulator of inflammation: Implications for various human pathologies

M Filková, M Haluzík, S Gay, L Šenolt - Clinical immunology, 2009 - Elsevier
Resistin was originally described as an adipocyte-secreted peptide that induced insulin
resistance in rodents. Increasing evidence indicates its important regulatory roles in various …

Adipocytokines: leptin—the classical, resistin—the controversical, adiponectin—the promising, and more to come

A Koerner, J Kratzsch, W Kiess - Best practice & research Clinical …, 2005 - Elsevier
With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has
been extended to the secretory products of adipocytes, since they are increasingly shown to …

Emerging role of adipocytokines in type 2 diabetes as mediators of insulin resistance and cardiovascular disease

R Jaganathan, R Ravindran… - Canadian journal of …, 2018 - Elsevier
Adipose tissue is an enormously active endocrine organ, secreting various hormones, such
as adiponectin, leptin, resistin and visfatin, together with classical cytokines, such as tumor …

Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome

SF de Medeiros, RJ Rodgers… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Metabolic and endocrine alterations in women with polycystic ovary
syndrome (PCOS) affect adipose tissue mass and distribution. PCOS is characterised by …

Roles of adipokines in digestive diseases: markers of inflammation, metabolic alteration and disease progression

ML Chang, Z Yang, SS Yang - International journal of molecular sciences, 2020 - mdpi.com
Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Resistin, a novel host defense peptide of innate immunity

Y Li, Q Yang, D Cai, H Guo, J Fang, H Cui… - Frontiers in …, 2021 - frontiersin.org
Resistin, a cysteine-rich protein, expressed in adipocytes, was initially proposed as a link
between obesity and diabetes in mice. In humans, resistin is considered to be a pro …

An update on the molecular and cellular basis of pharmacotherapy in type 2 diabetes mellitus

MO Mahgoub, II Ali, JO Adeghate, K Tekes… - International journal of …, 2023 - mdpi.com
Diabetes mellitus (DM) is a chronic illness with an increasing global prevalence. More than
537 million cases of diabetes were reported worldwide in 2021, and the number is steadily …

[HTML][HTML] Lipid metabolism disorder promotes the development of intervertebral disc degeneration

J Yi, Q Zhou, J Huang, S Niu, G Ji, T Zheng - Biomedicine & …, 2023 - Elsevier
Lipid metabolism is a complex process that maintains the normal physiological function of
the human body. The disorder of lipid metabolism has been implicated in various human …