In recent years, there has been an explosion of interest in how fibroblasts initiate, sustain,
and resolve inflammation across disease states. Fibroblasts contain heterogeneous subsets …

Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

Background: This document updates the American Thoracic Society/European Respiratory
Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on …

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic,
progressive scarring of the lungs and the pathological hallmark of usual interstitial …

Lipid nanoparticle-assisted mRNA inhalation therapy necessitates addressing challenges
such as resistance to shear force damage, mucus penetration, cellular internalization, rapid …

Background A combination of prednisone, azathioprine, and N-acetylcysteine (NAC) has
been widely used as a treatment for idiopathic pulmonary fibrosis. The safety and efficacy of …

This document is an international evidence-based guideline on the diagnosis and
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …

Abstract N-acetyl-l-cysteine (NAC) has long been used therapeutically for the treatment of
acetaminophen (paracetamol) overdose, acting as a precursor for the substrate (l-cysteine) …

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

Background Idiopathic pulmonary fibrosis is a progressive and fatal lung disease with
inevitable loss of lung function. The CAPACITY programme (studies 004 and 006) was …