Pathophysiology, diagnosis, and management of endometriosis

AW Horne, SA Missmer - bmj, 2022 - bmj.com
Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

Endometriosis: Etiology, pathobiology, and therapeutic prospects

PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

N Rahmioglu, S Mortlock, M Ghiasi, PL Møller… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

Hormonal treatments for endometriosis: The endocrine background

S Vannuccini, S Clemenza, M Rossi… - Reviews in Endocrine and …, 2022 - Springer
Endometriosis is a benign uterine disorder characterized by menstrual pain and infertility,
deeply affecting women's health. It is a chronic disease and requires a long term …

Rethinking mechanisms, diagnosis and management of endometriosis

C Chapron, L Marcellin, B Borghese… - Nature Reviews …, 2019 - nature.com
Endometriosis is a chronic inflammatory disease defined as the presence of endometrial
tissue outside the uterus, which causes pelvic pain and infertility. This disease should be …

[HTML][HTML] Pathogenesis of endometriosis: the origin of pain and subfertility

TM Gruber, S Mechsner - Cells, 2021 - mdpi.com
Endometriosis (EM) and adenomyosis (AM) are common conditions with pain and infertility
as the principal symptoms. The pathophysiology of pain in EM and AM comprises sensory …

What we know about primary dysmenorrhea today: a critical review

S Iacovides, I Avidon, FC Baker - Human reproduction update, 2015 - academic.oup.com
BACKGROUND Primary dysmenorrhea, or painful menstruation in the absence of pelvic
pathology, is a common, and often debilitating, gynecological condition that affects between …

Impact of endometriosis on life-course potential: a narrative review

SA Missmer, FF Tu, SK Agarwal… - … journal of general …, 2021 - Taylor & Francis
Endometriosis may exert a profound negative influence on the lives of individuals with the
disorder, adversely affecting quality of life, participation in daily and social activities, physical …

A lifelong impact on endometriosis: pathophysiology and pharmacological treatment

LH Chen, WC Lo, HY Huang, HM Wu - International journal of molecular …, 2023 - mdpi.com
Endometriosis is a chronic inflammatory disease associated with bothersome symptoms in
premenopausal women and is complicated with long-term systemic impacts in the post …