The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

Much of the mammalian skeleton is composed of bones that originate from cartilage
templates through endochondral ossification. Elucidating the mechanisms that control …

Autosomal dominant mutations in fibroblast growth factor receptor 3 (FGFR3) cause
achondroplasia (Ach), the most common form of dwarfism in humans, and related …

Fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) signaling plays
essential roles in bone development and diseases. Missense mutations in FGFs and FGFRs …

Over the last decade the identification of mutations in the receptors for fibroblast growth
factors (FGFs) has defined essential roles for FGF signaling in both endochondral and …

The fibroblast growth factor (Fgf) family of ligands and receptor tyrosine kinases is required
throughout embryonic and postnatal development and also regulates multiple homeostatic …

Endochondral ossification begins from the condensation and differentiation of mesenchymal
cells into cartilage. The cartilage then goes through a program of cell proliferation …

Tumour stage was defined using TNM and FIGO classifications for bladder and cervix
carcinomas, respectively; Mostofi's histopathological grading system was used for bladder …

Human craniosynostosis syndromes, resulting from activating or neomorphic mutations in
fibroblast growth factor receptor 2 (FGFR2), underscore an essential role for FGFR2 …

Fibroblast growth factors (FGFs) are key regulators of several developmental processes in
which cell fate and differentiation to various tissue lineages are determined. The importance …