Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …

The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

The gut microbiota has emerged as an environmental factor that modulates the development
of the central nervous system (CNS) and the enteric nervous system (ENS). Before obtaining …

Enteric glia are the partners of neurons in the enteric nervous system throughout the
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …

The intestinal epithelium is a rapidly renewing cellular compartment. This constant
regeneration is a hallmark of intestinal homeostasis and requires a tightly regulated balance …

The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …

Lewy pathology affects the gastrointestinal tract in Parkinson's disease (PD) and data from
recent genetic studies suggest a link between PD and gut inflammation. We therefore …

The interplay between the immune and nervous systems has been acknowledged in the
past, but only more recent studies have started to unravel the cellular and molecular players …

The intestinal microbiota, which is composed of bacteria, viruses, and micro-eukaryotes, acts
as an accessory organ system with distinct functions along the intestinal tract that are critical …