Intermittent hypoxemia and OSA: implications for comorbidities
NA Dewan, FJ Nieto, VK Somers - Chest, 2015 - Elsevier
OSA is a common chronic disorder that is associated with significant morbidity and mortality
including cardiovascular, metabolic, and neurocognitive disease and increased cancer …
including cardiovascular, metabolic, and neurocognitive disease and increased cancer …
Obstructive sleep apnea and comorbidities: a dangerous liaison
MR Bonsignore, P Baiamonte, E Mazzuca… - Multidisciplinary …, 2019 - Springer
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated
with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged …
with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged …
International consensus statement on obstructive sleep apnea
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …
allows for consolidation and determination of the key factors important for clinical …
Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome
Objective: To provide an overview of the healthcare and societal consequences and costs of
untreated obstructive sleep apnea syndrome. Data sources: PubMed database for English …
untreated obstructive sleep apnea syndrome. Data sources: PubMed database for English …
Hypoxia-inducible factors and cancer
Abstract Purpose of Review Hypoxia-inducible factors (HIFs) mediate the transcription of
hundreds of genes that allow cells to adapt to hypoxic environments. In this review, we …
hundreds of genes that allow cells to adapt to hypoxic environments. In this review, we …
ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia
Y Chao, J Shang, W Ji - Biochemical and biophysical research …, 2020 - Elsevier
Obstructive sleep apnea (OSA) is closely associated with cancer progression and cancer-
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …
Sleep apnea and cancer: analysis of a nationwide population sample
Abstract Study Objectives: Epidemiological evidence from relatively small cohorts suggests
that obstructive sleep apnea (OSA) is associated with higher cancer incidence and mortality …
that obstructive sleep apnea (OSA) is associated with higher cancer incidence and mortality …
Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer
I Hunyor, KM Cook - American Journal of Physiology …, 2018 - journals.physiology.org
Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …
Obstructive sleep apnea and incident cancer: a large retrospective multicenter clinical cohort study
Background: To examine the association between the severity of obstructive sleep apnea
(OSA) and nocturnal hypoxemia with incident cancer. Methods: This was a multicenter …
(OSA) and nocturnal hypoxemia with incident cancer. Methods: This was a multicenter …
Obesity, sleep apnea, and cancer
The interest on a potential association between cancer and sleep-disordered breathing
(SDB) has clearly gained substantial traction over the last several years. This novel …
(SDB) has clearly gained substantial traction over the last several years. This novel …