BACKGROUND Numerous studies have reported CFTR mutations in CBAVD (congenital
bilateral absence of the vas deferens) patients, but their results are not completely …

BACKGROUND The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-
activated Cl− and HCO3− conducting channel, mutations of which are known to be …

Several diseases have been clinically or genetically related to cystic fibrosis (CF), but a
consensus definition is lacking. Here, we present a proposal for consensus guidelines on …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

Congenital bilateral absence of the vas deferens (CBAVD) is a form of infertility with an
autosomal recessive genetic background in otherwise healthy males. CBAVD is caused by …

BACKGROUND Our previous studies have demonstrated the cystic fibrosis transmembrane
conductance regulator (CFTR) is important for capacitation and male fertility in mouse and …

Cystic fibrosis (CF) is the most common life-limiting recessive genetic disease among
Caucasians caused by mutations of the cystic fibrosis transmembrane conductance …

Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl−
channel expressed in a wide variety of epithelial cells, mutations of which are responsible …

OBJECTIVE: To investigate the frequency of mutations of the cystic fibrosis transmembrane
regulator (CFTR) gene in males with reduced sperm quality before intracytoplasmic sperm …

Spermatogenesis is a multistep process that supports the production of millions of sperm
daily. Understanding of the molecular mechanisms that regulate spermatogenesis has been …