Quorum sensing inhibitors as antipathogens: biotechnological applications

VC Kalia, SKS Patel, YC Kang, JK Lee - Biotechnology advances, 2019 - Elsevier
The mechanisms through which microbes communicate using signal molecules has inspired
a great deal of research. Microbes use this exchange of information, known as quorum …

Quorum quenching: role in nature and applied developments

C Grandclément, M Tannières, S Moréra… - FEMS microbiology …, 2016 - academic.oup.com
Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density
and regulate gene expression accordingly: the QS-regulated processes deal with …

Bacterial quorum sensing: its role in virulence and possibilities for its control

ST Rutherford, BL Bassler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …

Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era

M Kostakioti, M Hadjifrangiskou… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …

Quorum sensing inhibitors: an overview

VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - Am Soc Microbiol
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

Predictors of mortality in Staphylococcus aureus bacteremia

SJ Van Hal, SO Jensen, VL Vaska… - Clinical microbiology …, 2012 - Am Soc Microbiol
Staphylococcus aureus bacteremia (SAB) is an important infection with an incidence rate
ranging from 20 to 50 cases/100,000 population per year. Between 10% and 30% of these …

Combating multidrug‐resistant bacteria: current strategies for the discovery of novel antibacterials

KMG O'Connell, JT Hodgkinson… - Angewandte Chemie …, 2013 - Wiley Online Library
The introduction of effective antibacterial therapies for infectious diseases in the mid‐20th
century completely revolutionized clinical practices and helped to facilitate the development …

Autoinduction and signal transduction in the regulation of staphylococcal virulence

RP Novick - Molecular microbiology, 2003 - Wiley Online Library
The accessory genes of Staphylococcus aureus, in‐cluding those involved in pathogenesis,
are controlled by a complex regulatory network that includes at least four two‐component …

Quorum sensing in staphylococci

RP Novick, E Geisinger - Annual review of genetics, 2008 - annualreviews.org
The staphylococcal agr locus encodes a quorum sensing (QS) system that controls the
expression of virulence and other accessory genes by a classical two-component signaling …