Chemokines, or chemotactic cytokines, and their receptors have been discovered as
essential and selective mediators in leukocyte migration to inflammatory sites and to …

G protein‐coupled chemokine receptors and their peptidergic ligands are interesting
therapeutic targets due to their involvement in various immune‐related diseases, including …

Chemokines form a sophisticated communication network wherein they maneuver the
spatiotemporal migration of immune cells across a system. These chemical messengers are …

Objectives: Early diagnosis and detection of acute rejection following kidney transplantation
are of great significance for guiding the treatment and improving the prognosis of renal …

One question in lymphocyte homing is how integrins are rapidly activated to enable
immediate arrest of fast rolling lymphocytes upon encountering chemokines at target …

Purpose: Breast carcinomas, including basal and hereditary cases, often present with a
prominent tumoral lymphocytic infiltrate. Chemokines could play a role in attracting these …

Background: GPCRs can activate selective signaling pathways according to the nature of
the bound ligand. Results: Coupling selectivity of chemokine receptors CCR2, CCR5, and …

Chemokines are a family of soluble cytokines that act as chemoattractants to guide the
migration of cells, in particular of immune cells. However, chemokines are also involved in …

Accumulating evidence reveals involvement of T lymphocytes and adaptive immunity in the
chronic inflammation associated with infectious and noninfectious diseases of the heart …

Interactions between chemokines and chemokine receptors have been proposed recently to
be of importance in the development and progression of cancer. Human breast cancer cells …