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[HTML][HTML] Metabolic syndrome: updates on pathophysiology and management in 2021
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation …
Obesity reaches up to epidemic proportions globally and increases the risk for a wide
spectrum of co-morbidities, including type-2 diabetes mellitus (T2DM), hypertension …
spectrum of co-morbidities, including type-2 diabetes mellitus (T2DM), hypertension …
Light exposure during sleep impairs cardiometabolic function
This study tested the hypothesis that acute exposure to light during nighttime sleep
adversely affects next-morning glucose homeostasis and whether this effect occurs via …
adversely affects next-morning glucose homeostasis and whether this effect occurs via …
Elevated levels of alcohol dehydrogenase aggravate ethanol-evoked cardiac remodeling and contractile anomalies through FKBP5-yap-mediated regulation of …
Q Lu, X Qin, C Chen, W Yu, J Lin, X Liu, R Guo… - Life Sciences, 2024 - Elsevier
Alcohol intake provokes severe organ injuries including alcoholic cardiomyopathy with
hallmarks of cardiac remodeling and contractile defects. This study examined the toxicity of …
hallmarks of cardiac remodeling and contractile defects. This study examined the toxicity of …
Sympathetic nervous system overactivity and its role in the development of cardiovascular disease
SC Malpas - Physiological reviews, 2010 - journals.physiology.org
This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …
regulation of cardiovascular function over multiple time scales. This is achieved through …
Estrogen-related mechanisms in sex differences of hypertension and target organ damage
AR Sabbatini, G Kararigas - Biology of sex differences, 2020 - Springer
Hypertension (HTN) is a primary risk factor for cardiovascular (CV) events, target organ
damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is …
damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is …
Slow-wave sleep and the risk of type 2 diabetes in humans
E Tasali, R Leproult, DA Ehrmann… - Proceedings of the …, 2008 - pnas.org
There is convincing evidence that, in humans, discrete sleep stages are important for
daytime brain function, but whether any particular sleep stage has functional significance for …
daytime brain function, but whether any particular sleep stage has functional significance for …
Inter‐related effects of insulin resistance, hyperandrogenism, sympathetic dysfunction and chronic inflammation in PCOS
S Shorakae, S Ranasinha, S Abell… - Clinical …, 2018 - Wiley Online Library
Objective Insulin resistance, hyperandrogenism, sympathetic dysfunction and chronic low‐
grade inflammation may act together in a vicious cycle in the pathophysiology of PCOS …
grade inflammation may act together in a vicious cycle in the pathophysiology of PCOS …
The relationship between shear stress and flow‐mediated dilatation: implications for the assessment of endothelial function
KE Pyke, ME Tschakovsky - The Journal of physiology, 2005 - Wiley Online Library
Endothelium‐dependent flow‐mediated dilatation (FMD) describes the vasodilatory
response of a vessel to elevations in blood flow‐associated shear stress. Nitric oxide (NO) …
response of a vessel to elevations in blood flow‐associated shear stress. Nitric oxide (NO) …
Sex and gender differences in control of blood pressure
R Maranon, JF Reckelhoff - Clinical science, 2013 - portlandpress.com
In recent years, the interest in studying the impact of sex steroids and gender on the
regulation of blood pressure and cardiovascular disease has been growing. Women are …
regulation of blood pressure and cardiovascular disease has been growing. Women are …