Over the past few decades, advances in hydrogel technologies have spurred development
in many biomedical applications including controlled drug delivery. Many novel hydrogel …

Most existing vaccines for human use are administered by needle-based injection.
Administering vaccines needle-free intranasally has numerous advantages over by needle …

Solid lipid particulate systems such as solid lipid nanoparticles (SLN), lipid microparticles
(LM) and lipospheres have been sought as alternative carriers for therapeutic peptides …

Therapeutic peptides/proteins and protein-based antigens are chemically and structurally
labile compounds, which are almost exclusively administered by parenteral injections …

In this study, the potential of N-trimethyl chitosan (TMC) nanoparticles as a carrier system for
the nasal delivery of proteins was investigated. TMC nanoparticles were prepared by ionic …

Purpose. The aim of the study was to encapsulate a model protein antigen, tetanus toxoid
(TT), within hydrophobic (PLA) and surface hydrophilic (PLA-PEG) nanoparticles and to …

BSA was entrapped in particles of different sizes (200, 500 and 1000nm) prepared from poly
(d, l-lactic-co-glycolic) acid by a double emulsion method. The particles were given, either …

Biodegradable polymer and particulate carriers have been shown to be of considerable
potential for the delivery of peptides, proteins and DNA in animal models. In the context of …

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there
were only 19 biotechology medicines on the market. Currently there are more than 100, with …

Absorption of drugs and vaccines at mucosal surfaces may be enhanced by conjugation to
appropriate bioadhesins which bind to mucosal epithelia. Bioadhesins might also permit cell …