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Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing
Abstract 'Smart'bandages based on multimodal wearable devices could enable real-time
physiological monitoring and active intervention to promote healing of chronic wounds …
physiological monitoring and active intervention to promote healing of chronic wounds …
[HTML][HTML] Navigating the collagen jungle: the biomedical potential of fiber organization in cancer
Recent research has highlighted the importance of key tumor microenvironment features,
notably the collagen-rich extracellular matrix (ECM) in characterizing tumor invasion and …
notably the collagen-rich extracellular matrix (ECM) in characterizing tumor invasion and …
[HTML][HTML] Recent advancements in optical harmonic generation microscopy: Applications and perspectives
S JamesDarian, J CampagnolaPaul - BME frontiers, 2021 - spj.science.org
Second harmonic generation (SHG) and third harmonic generation (THG) microscopies
have emerged as powerful imaging modalities to examine structural properties of a wide …
have emerged as powerful imaging modalities to examine structural properties of a wide …
Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis
AL Wishart, SJ Conner, JR Guarin, JP Fatherree… - Science …, 2020 - science.org
The extracellular matrix (ECM), a major component of the tumor microenvironment,
promotes local invasion to drive metastasis. Here, we describe a method to study whole …
promotes local invasion to drive metastasis. Here, we describe a method to study whole …
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting
Burns and other traumatic injuries represent a substantial biomedical burden. The current
standard of care for deep injuries is autologous split-thickness skin grafting (STSG), which …
standard of care for deep injuries is autologous split-thickness skin grafting (STSG), which …
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease. Recent
findings have shown a marked metabolic reprogramming associated with changes in …
findings have shown a marked metabolic reprogramming associated with changes in …
Disrupting biological sensors of force promotes tissue regeneration in large organisms
Tissue repair and healing remain among the most complicated processes that occur during
postnatal life. Humans and other large organisms heal by forming fibrotic scar tissue with …
postnatal life. Humans and other large organisms heal by forming fibrotic scar tissue with …
Pullulan‐Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings
Biological scaffolds such as hydrogels provide an ideal, physio‐mimetic of native
extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury …
extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury …
The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation
V Vorstandlechner, M Laggner, D Copic, K Klas… - Nature …, 2021 - nature.com
Despite recent advances in understanding skin scarring, mechanisms triggering
hypertrophic scar formation are still poorly understood. In the present study, we investigate …
hypertrophic scar formation are still poorly understood. In the present study, we investigate …
Collagen Alignment as a Predictor of Recurrence after Ductal Carcinoma In Situ
Background: Collagen fibers surrounding breast ducts may influence breast cancer
progression. Syndecan-1 interacts with constituents in the extracellular matrix, including …
progression. Syndecan-1 interacts with constituents in the extracellular matrix, including …