Design, synthesis and docking studies of novel thiazole derivatives incorporating pyridine moiety and assessment as antimicrobial agents
A novel series of substituted 4, 6-dimethyl-2-oxo-1-(thiazol-2-ylamino)-1, 2-dihydropyridine-
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …
Design, one-pot synthesis, in silico ADMET prediction and molecular docking of novel triazolyl thiadiazine and thiazole derivatives with evaluation of antimicrobial …
A facile one pot multi-component synthesis of novel 1, 3, 4-thiadiazine and thiazole
derivatives from the reaction of (methyl-1-(p-tolyl)-1 H-1, 2, 3-triazol-4-yl) ethan-1-one …
derivatives from the reaction of (methyl-1-(p-tolyl)-1 H-1, 2, 3-triazol-4-yl) ethan-1-one …
Synthesis and antibacterial evaluation of novel mono- and bis(2H-chromen-2-imine) hybrids linked to heteroarene units
Novel mono-and bis (2H-chromen-2-imine) hybrids linked to different heteroarene units
were prepared by cyclocondensation of 2-hydroxybenzaldehydes with 2 …
were prepared by cyclocondensation of 2-hydroxybenzaldehydes with 2 …
Utilization of 2-cyano-N-(2, 5-dioxopyrrolidin-1-yl) acetamide for the synthesis of thiazole, pyrazole and pyridene derivatives with a biological evaluation
MAMA Reheim, ISA Hafiz, RM Darweesh… - Journal of the Iranian …, 2024 - Springer
A range of fused heterocyclic compounds are generated utilizing the crucial intermediary 2-
cyano-N-(2, 5-dioxopyrrolidin-1-yl) acetamide 4. Spectral analysis was executed to support …
cyano-N-(2, 5-dioxopyrrolidin-1-yl) acetamide 4. Spectral analysis was executed to support …
Synthesis, molecular docking, and antitumor evaluation of some new pyrazole, pyridine, and thiazole derivatives incorporating sulfonamide residue
Cancer is the second leading cause of death worldwide. There is always a huge demand for
novel anticancer. New series of pyrazole, pyridine, thiazole derivatives containing …
novel anticancer. New series of pyrazole, pyridine, thiazole derivatives containing …