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Memory engrams: Recalling the past and imagining the future
BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …
Transcending time in the brain: How event memories are constructed from experience
Our daily lives unfold continuously, yet when we reflect on the past, we remember those
experiences as distinct and cohesive events. To understand this phenomenon, early …
experiences as distinct and cohesive events. To understand this phenomenon, early …
Predictions transform memories: How expected versus unexpected events are integrated or separated in memory
Our brains constantly generate predictions about the environment based on prior
knowledge. Many of the events we experience are consistent with these predictions, while …
knowledge. Many of the events we experience are consistent with these predictions, while …
Memory allocation: mechanisms and function
Memories for events are thought to be represented in sparse, distributed neuronal
ensembles (or engrams). In this article, we review how neurons are chosen to become part …
ensembles (or engrams). In this article, we review how neurons are chosen to become part …
The brain in motion: How ensemble fluidity drives memory-updating and flexibility
While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …
simply conserve veridical representations of the past but must continually integrate new …
Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system
How memories are organized in the brain influences whether they are remembered
discretely versus linked with other experiences or whether generalized information is …
discretely versus linked with other experiences or whether generalized information is …
Brain mechanisms of concept learning
Concept learning, the ability to extract commonalities and highlight distinctions across a set
of related experiences to build organized knowledge, is a critical aspect of cognition …
of related experiences to build organized knowledge, is a critical aspect of cognition …
Generalization and the hippocampus: More than one story?
Memory-based cognition depends on both the ability to remember specific details of
individual experiences and the ability to combine information across experiences to …
individual experiences and the ability to combine information across experiences to …
Engram mechanisms of memory linking and identity
Memories are thought to be stored in neuronal ensembles referred to as engrams. Studies
have suggested that when two memories occur in quick succession, a proportion of their …
have suggested that when two memories occur in quick succession, a proportion of their …
Representations of common event structure in medial temporal lobe and frontoparietal cortex support efficient inference
Prior work has shown that the brain represents memories within a cognitive map that
supports inference about connections between individual related events. Real-world …
supports inference about connections between individual related events. Real-world …