Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small
arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular
diseases primarily affecting small arteries, capillaries, arterioles and venules. The diagnosis …

Stroke is a major cause of death and adult disability. However, therapeutic options remain
limited. Numerous pathways underlie acute responses of brain tissue to stroke. Early events …

The brain is one of the most exquisite organs in the body with high metabolic demands, and
requires a tight regulation of the surrounding environment. This tight control is exerted by the …

With the coming acceleration of global population aging, the incidence rate of cardio-
cerebrovascular diseases (CVDs) is increasing. It has become the leading cause of human …

Blood-brain barrier disruption plays an important role in central nervous system diseases.
This review provides information on the role of mitochondrial oxidative stress in brain …

Incident stroke has long been recognized to cause dementia shortly after the event. Patients
who survive stroke without early-onset poststroke dementia (PSD) are at a high risk of …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that produces a
selective loss of the motor neurons of the spinal cord, brain stem and motor cortex. Oxidative …

Objective: Alzheimer's disease and vascular dementia are responsible for more than 80% of
dementia cases. These two conditions share common risk factors including hypertension …