Tumour‐associated neutrophils: Potential therapeutic targets in pancreatic cancer immunotherapy

Q Wu, H Mao, Z Jiang, D Tang - Immunology, 2024‏ - Wiley Online Library
Pancreatic cancer (PC) is a highly malignant tumour of the digestive system with poor
therapeutic response and low survival rates. Immunotherapy has rapidly developed in …

Prognosis stratification of cancer patients treated with immune checkpoint inhibitors through lung immune prognostic index: a meta-analysis and systematic review

Y Guo, Y Pan, J Wan, B Gong, Y Li, X Kan, C Zheng - BMC cancer, 2024‏ - Springer
Background Although numerous studies have reported the prognostic value of the lung
immune prognostic index (LIPI) in non-small cell lung cancer (NSCLC) patients treated with …

An epitope encoded by uORF of RNF10 elicits a therapeutic anti-tumor immune response

L Zeng, W Zheng, J Zhang, J Wang, Q Ji, X Wu… - Molecular Therapy …, 2023‏ - cell.com
Tumor-specific antigens (TSAs) are crucial for tumor-specific immune response that reduces
tumor burden and thus serve as important targets for immunotherapy. Identification of novel …

Machine learning models for predicting of PD-1 treatment efficacy in Pan-cancer patients based on routine hematologic and biochemical parameters

W Yang, C Chen, Q Ouyang, R Han, P Sun… - Cancer Cell …, 2024‏ - Springer
Immune checkpoint blockade therapy targeting the programmed death-1 (PD-1) pathway
has shown remarkable efficacy and durable response in patients with various cancer types …

Application of alkaline phosphatase-to-hemoglobin and lactate dehydrogenase-to-hemoglobin ratios as novel noninvasive indices for predicting severe acute …

SY Chen, XJ Song, JT Lu, JX Liang, H Ouyang… - PloS one, 2024‏ - journals.plos.org
Preventing the progression of acute pancreatitis (AP) to severe acute pancreatitis (SAP) is
crucial for AP patients. The use of clinical parameters in laboratory facilities for predicting …