Endothelial dysfunction, the shift from a healthy endothelium to a damaged pro-coagulative,
pro-inflammatory, and pro-vasoconstrictive phenotype, is an early event in many chronic …

Aptamers are synthetic molecules structured as single-stranded DNA or RNA
oligonucleotides that can be designed to mimic the functional properties of monoclonal …

Several systemic diseases, including thrombotic thrombocytopenic purpura, manifest much
of their pathology through activation of endothelium and thrombotic occlusion of small blood …

Platelet inhibitors are the mainstay treatment for patients with vascular diseases. The current
'gold standard'antiplatelet agent clopidogrel has several pharmacological and clinical …

Background: Providing care to a spouse with Alzheimer's disease (AD) may contribute to
cardiovascular disease (CVD). The acute phase reactant C-reactive protein (CRP) is a well …

A sufficiently low level of von Willebrand factor (VWF) predisposes to bleeding that can be
quite serious, and low VWF is a diagnostic feature of von Willebrand disease (VWD) type 1 …

Time‐dependent changes of protein biomarkers in the cerebrospinal fluid (CSF) can be
used to identify the pathological processes in traumatic brain injury (TBI) as well as to follow …

Objective Cardiovascular illnesses have been associated to ABO blood types, specifically
through an effect on von Willebrand factor and factor FVIII levels. We conducted a meta …

ABO blood type is one of the most readily available laboratory tests, and serves as a vital
determinant in blood transfusion and organ transplantation. The ABO antigens are …

Introduction von Willebrand factor (VWF) plays a critical role in platelet adhesion and
aggregation after vascular injury and at sites of high shear rate. Elevated VWF levels are …