Diabetic corneal neuropathy
Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …
Body fluid biomarkers for Alzheimer's disease—an up-to-date overview
Neurodegeneration is a highly complex process which is associated with a variety of
molecular mechanisms related to ageing. Among neurodegenerative disorders, Alzheimer's …
molecular mechanisms related to ageing. Among neurodegenerative disorders, Alzheimer's …
Tear film and ocular surface neuropeptides: Characteristics, synthesis, signaling and implications for ocular surface and systemic diseases
Ocular surface neuropeptides are vital molecules primarily involved in maintaining ocular
surface integrity and homeostasis. They also serve as communication channels between the …
surface integrity and homeostasis. They also serve as communication channels between the …
Leukocyte glucose index as a novel biomarker for COVID-19 severity
WM Ramos-Hernández, LF Soto… - Scientific Reports, 2022 - nature.com
The severity of coronavirus disease 2019 (COVID-19) quickly progresses with unfavorable
outcomes due to the host immune response and metabolism alteration. Hence, we …
outcomes due to the host immune response and metabolism alteration. Hence, we …
[HTML][HTML] Potential underlying genetic associations between keratoconus and diabetes mellitus
KM Ates, AJ Estes, Y Liu - Advances in ophthalmology practice and …, 2021 - Elsevier
Background Keratoconus (KC) is the most common ectatic corneal disease, characterized
by significantly localized thinning of the corneal stroma. Genetic, environmental, hormonal …
by significantly localized thinning of the corneal stroma. Genetic, environmental, hormonal …
Bio-chemical markers of chronic, non-infectious disease in the human tear film
The tear film is a thin, moist layer covering the ocular surface and is laden with proteins,
peptides, lipids, mucins, electrolytes and cellular debris which function to maintain the …
peptides, lipids, mucins, electrolytes and cellular debris which function to maintain the …
Chronic kidney disease has no impact on tear film substance p concentration in type 2 diabetes
Purpose: The study aimed to ascertain the potential effects of chronic kidney disease (CKD)
on substance P concentration in the tear film of people with type 2 diabetes. Methods …
on substance P concentration in the tear film of people with type 2 diabetes. Methods …
Screening of pathologically significant diagnostic biomarkers in tears of thyroid eye disease based on bioinformatic analysis and machine learning
X Shu, C Zeng, Y Zhu, Y Chen, X Huang… - Frontiers in Cell and …, 2024 - frontiersin.org
Background Lacrimal gland enlargement is a common pathological change in patients with
thyroid eye disease (TED). Tear fluid has emerged as a new source of diagnostic …
thyroid eye disease (TED). Tear fluid has emerged as a new source of diagnostic …
[HTML][HTML] Effects of the Topical Use of the Natural Antioxidant Alpha-Lipoic Acid on the Ocular Surface of Diabetic Patients with Dry Eye Symptoms
AM Roszkowska, R Spinella, GW Oliverio… - Frontiers in Bioscience …, 2022 - imrpress.com
Purpose: The purpose of this study is to investigate the effects of the treatment with eye-
drops based on a combination of antioxidant and mucomimetic molecules, namely 0.1 …
drops based on a combination of antioxidant and mucomimetic molecules, namely 0.1 …
Tear matrix metalloproteinases-9 and ocular surface parameters in diabetics: a cross-sectional study in Shenyang, China
Z Qu, EE Pazo, L Yang, J Chen, G Qin, W He - BMJ open, 2025 - bmjopen.bmj.com
Background Overexpression of tear matrix metalloproteinases-9 (MMP-9) on the ocular
surface tissues has been reported to result in ocular surface damage. MMP-9 levels in tears …
surface tissues has been reported to result in ocular surface damage. MMP-9 levels in tears …