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Liquid chromatography–tandem mass spectrometry for clinical diagnostics
Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of
substances and matrices; it is increasingly utilized for clinical applications in laboratory …
substances and matrices; it is increasingly utilized for clinical applications in laboratory …
Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories
AG Birhanu - Clinical proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …
Emerging applications of metabolomics in drug discovery and precision medicine
DS Wishart - Nature reviews Drug discovery, 2016 - nature.com
Metabolomics is an emerging'omics' science involving the comprehensive characterization
of metabolites and metabolism in biological systems. Recent advances in metabolomics …
of metabolites and metabolism in biological systems. Recent advances in metabolomics …
Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system
Conventional methods for histopathologic tissue diagnosis are labor-and time-intensive and
can delay decision-making during diagnostic and therapeutic procedures. We report the …
can delay decision-making during diagnostic and therapeutic procedures. We report the …
Spatially resolved metabolomics to discover tumor-associated metabolic alterations
Characterization of tumor metabolism with spatial information contributes to our
understanding of complex cancer metabolic reprogramming, facilitating the discovery of …
understanding of complex cancer metabolic reprogramming, facilitating the discovery of …
Molecular networking as a drug discovery, drug metabolism, and precision medicine strategy
Molecular networking is a tandem mass spectrometry (MS/MS) data organizational
approach that has been recently introduced in the drug discovery, metabolomics, and …
approach that has been recently introduced in the drug discovery, metabolomics, and …
Overview of mass spectrometry-based metabolomics: opportunities and challenges
The field of metabolomics has witnessed an exponential growth in the last decade driven by
important applications spanning a wide range of areas in the basic and life sciences and …
important applications spanning a wide range of areas in the basic and life sciences and …
Rapid evaporative ionisation mass spectrometry of electrosurgical vapours for the identification of breast pathology: towards an intelligent knife for breast cancer …
Background Re-operation for positive resection margins following breast-conserving surgery
occurs frequently (average= 20–25%), is cost-inefficient, and leads to physical and …
occurs frequently (average= 20–25%), is cost-inefficient, and leads to physical and …