Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

Biophotonics has seen significant advancements with the development of optical imaging
techniques facilitating the noninvasive detection of biologically relevant species …

Advancements in early detection have demonstrated the significance of biomarkers as
indicators of health and disease. Traditional detection methods often face limitations, such …

Near-infrared (NIR) aggregation-induced emission luminogens (AIEgens) are excellent
probes for tumor imaging, but there still is space to improve their imaging specificity and …

Extracellular vesicles (EVs) are emerging biomarkers in liquid biopsy that have gained
increasing attention in disease diagnosis and prognosis monitoring. Most reported detection …

With high efficiency, mild conditions, and rapid reaction rate, click reactions have garnered
much attention in the field of bioimaging since proposed by Sharpless et al. in 2001 (Angew …

Enzymatic molecular in situ self-assembly (E-MISA) that enables the synthesis of high-order
nanostructures from synthetic small molecules inside a living subject has emerged as a …

Bioorthogonal chemistry-mediated self-assembly holds great promise for dynamic molecular
imaging in living organisms. However, existing approaches are limited to nanoaggregates …

The abnormal aggregation of Aβ proteins, inflammatory responses, and mitochondrial
dysfunction have been reported as major targets in Alzheimer's disease (AD) …

A striking issue is the scarcity of imaging probes for the early diagnosis of Alzheimer's
disease. For the development of Aβ biomarkers, a mitochondria targeting, de novo …