Lipases: Useful biocatalysts for the preparation of pharmaceuticals
Biocatalysis offers a clean and ecological way to perform chemical processes, in mild
reaction conditions and with high degree of selectivity. The use of enzymes, specially …
reaction conditions and with high degree of selectivity. The use of enzymes, specially …
Application of lipases in kinetic resolution of racemates
Lipases have been well established as valuable catalysts in organic synthesis. This review
article focuses on some of the recent developments in the rapidly growing field of lipase …
article focuses on some of the recent developments in the rapidly growing field of lipase …
Trends in lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds
Over the last few years, there has been a dramatic increase in the number of publications in
the field of lipase-catalyzed reactions performed in common organic solvents, ionic liquids or …
the field of lipase-catalyzed reactions performed in common organic solvents, ionic liquids or …
Lipase-mediated chiral resolution of racemates in organic solvents
Lipase-catalyzed kinetic resolution of racemates is considered to be one of the most
fascinating topics in asymmetric catalysis. This review focuses on some of the recent …
fascinating topics in asymmetric catalysis. This review focuses on some of the recent …
Lipases: An overview of its current challenges and prospectives in the revolution of biocatalysis
Over the past few years most of the biochemical industries are in a rapid stage of
development. The major root cause responsible for this current state of excitement is a new …
development. The major root cause responsible for this current state of excitement is a new …
Enzymatic resolution of (±)-trans-4-(4′-fluorophenyl)-6-oxo-piperidin-3-ethyl carboxylate, an intermediate in the synthesis of (−)-Paroxetine
The enantioselective hydrolysis of (±)-trans-4-(4′-fluorophenyl)-6-oxo-piperidin-3-ethyl
carboxylate using four different microbial lipases was examined. This ester was found to be …
carboxylate using four different microbial lipases was examined. This ester was found to be …
Enzymatic kinetic resolution of primary alcohols by direct esterification in solvent-free system
R Irimescu, T Saito, K Kato - Journal of Molecular Catalysis B: Enzymatic, 2004 - Elsevier
Direct enzymatic esterification catalyzed by immobilized Candida antarctica lipase B (CALB)
and Rhizomucor miehei lipase (RML) was evaluated for kinetic resolution of some primary …
and Rhizomucor miehei lipase (RML) was evaluated for kinetic resolution of some primary …
Kinetic resolution of (R/S)-propranolol (1-isopropylamino-3-(1-naphtoxy)-2-propanolol) catalyzed by immobilized preparations of Candida antarctica lipase B (CAL-B)
Enzyme preparations of Candida antarctica B lipase (CAL-B)–immobilized on Eupergit C
and partially modified Eupergit C supports–were tested for kinetic resolution of (R/S) …
and partially modified Eupergit C supports–were tested for kinetic resolution of (R/S) …
Silylium‐Catalyzed Alkynylation and Etherification Reactions of Benzylic Acetates
B Rubial, A Ballesteros… - European Journal of …, 2022 - Wiley Online Library
Addition of catalytic amounts of bistriflimide triggers useful coupling reactions of benzyl
acetates with trimethyl (alkynyl) silanes and trimethyl (alkoxy) silanes to afford propargyl …
acetates with trimethyl (alkynyl) silanes and trimethyl (alkoxy) silanes to afford propargyl …
Enzymatic esterification of lavandulol – a partial kinetic resolution of (S)-lavandulol and preparation of optically enriched (R)-lavandulyl acetate
The asymmetric esterification of the racemic primary alcohol lavandulol was achieved using
lipase B from Candida antarctica and acetic acid as acyl donor in 80% yield. The …
lipase B from Candida antarctica and acetic acid as acyl donor in 80% yield. The …