Updates of risk factors for anastomotic leakage after colorectal surgery
Anastomotic leakage is a potentially severe complication occurring after colorectal surgery
and can lead to increased morbidity and mortality, permanent stoma formation, and cancer …
and can lead to increased morbidity and mortality, permanent stoma formation, and cancer …
Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials
EF Giunta, G Bregni, A Pretta, A Deleporte… - Cancer treatment …, 2021 - Elsevier
A few months ago, results from two randomised phase III trials of total neoadjuvant therapy
(TNT) in locally advanced rectal cancer were presented (RAPIDO and PRODIGE 23) …
(TNT) in locally advanced rectal cancer were presented (RAPIDO and PRODIGE 23) …
Radiation therapy for rectal cancer: executive summary of an ASTRO clinical practice guideline
JY Wo, CJ Anker, JB Ashman, NA Bhadkamkar… - Practical radiation …, 2021 - Elsevier
Purpose This guideline reviews the evidence and provides recommendations for the
indications and appropriate technique and dose of neoadjuvant radiation therapy (RT) in the …
indications and appropriate technique and dose of neoadjuvant radiation therapy (RT) in the …
Outcome measures in multimodal rectal cancer trials
There is a large variability regarding the definition and choice of primary endpoints in phase
2 and phase 3 multimodal rectal cancer trials, resulting in inconsistency and difficulty of data …
2 and phase 3 multimodal rectal cancer trials, resulting in inconsistency and difficulty of data …
Gastrointestinal malignancies and the COVID-19 pandemic: evidence-based triage to surgery
Background The COVID-19 pandemic has led to widespread cancelation of electively
scheduled surgeries, including for colorectal, pancreatic, and gastric cancer. The American …
scheduled surgeries, including for colorectal, pancreatic, and gastric cancer. The American …
[HTML][HTML] How to measure tumour response in rectal cancer? An explanation of discrepancies and suggestions for improvement
Various methods categorize tumour response after neoadjuvant therapy, including down-
staging and tumour regression grading. Response categories allow comparison of different …
staging and tumour regression grading. Response categories allow comparison of different …
Meta-analysis of the effect of extending the interval after long-course chemoradiotherapy before surgery in locally advanced rectal cancer
Background The current standard of care in locally advanced rectal cancer (LARC) is
neoadjuvant long-course chemoradiotherapy (nCRT) followed by total mesorectal excision …
neoadjuvant long-course chemoradiotherapy (nCRT) followed by total mesorectal excision …
Total neoadjuvant therapy versus standard neoadjuvant treatment strategies for the management of locally advanced rectal cancer: network meta-analysis of …
M Donnelly, OK Ryan, ÉJ Ryan, B Creavin… - British Journal of …, 2023 - academic.oup.com
Background This study compared the advantages and disadvantages of total neoadjuvant
therapy (TNT) strategies for patients with locally advanced rectal cancer, compared with the …
therapy (TNT) strategies for patients with locally advanced rectal cancer, compared with the …
Machine learning for predicting pathological complete response in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy
CM Huang, MY Huang, CW Huang, HL Tsai, WC Su… - Scientific reports, 2020 - nature.com
For patients with locally advanced rectal cancer (LARC), achieving a pathological complete
response (pCR) after neoadjuvant chemoradiotherapy (CRT) provides them with the optimal …
response (pCR) after neoadjuvant chemoradiotherapy (CRT) provides them with the optimal …
Randomized controlled trial of 8 weeks' vs 12 weeks' interval between neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer
Aim The aim was to compare the pathological complete response (pCR) rate at 8 compared
to 12 weeks' interval between completion of neoadjuvant chemoradiotherapy (CRT) and …
to 12 weeks' interval between completion of neoadjuvant chemoradiotherapy (CRT) and …