Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Protein subcellular localization is tightly controlled and intimately linked to protein function in
health and disease. Capturing the spatial proteome—that is, the localizations of proteins and …

Protein phosphorylation is a key post-translational modification regulating protein function in
almost all cellular processes. Although tens of thousands of phosphorylation sites have …

Background Non-alcoholic fatty liver disease (NAFLD) is defined by the abundance of lipid
droplets (LDs) in hepatocytes. While historically considered simply a depot for energy …

The liver performs numerous vital functions, including the detoxification of blood before
access to the brain while simultaneously secreting and internalizing scores of proteins and …

Protein phosphorylation is a major regulator of protein function and biological outcomes.
This was first recognized through functional biochemical experiments, and in the past …

In cells, lipids are stored in lipid droplets, dynamic organelles that adapt their size,
abundance, lipid and protein composition and organelle interactions to metabolic changes …

After having been disregarded for a long time as inert fat drops, lipid droplets (LDs) are now
recognized as ubiquitous cellular organelles with key functions in lipid biology and beyond …

Non-alcoholic fatty liver disease (NAFLD) is a multifaceted metabolic disorder, whose
spectrum covers clinical, histological and pathophysiological developments ranging from …

Diabetic cataract (DC) surgery carries risks such as slow wound healing, macular edema,
and progression of retinopathy and is faced with a deficiency of effective drugs. In this …