T cell lineages are defined by specialized functions and differential expression of surface
antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the …

Invariant natural killer T cells (iNKT cells) are an innate-like T cell subset that expresses an
invariant T cell receptor (TCR) α-chain and recognizes lipids presented on CD1d. They …

While most studies of T lymphocytes have focused on T cells reactive to complexes of
peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do …

Mucosal-associated invariant T cells (MAIT cells) detect microbial vitamin B2 derivatives
presented by the antigen-presenting molecule MR1. Here we defined three developmental …

Recognized more than a decade ago, NKT cells differentiate from mainstream thymic
precursors through instructive signals emanating during TCR engagement by CD1d …

Mucosal-associated invariant T (MAIT) cells harbor evolutionarily conserved TCRs,
suggesting important functions. As human and mouse MAIT functional programs appear …

Natural killer T cells (NKT cells) are CD1d-restricted, lipid antigen–reactive,
immunoregulatory T lymphocytes that can promote cell-mediated immunity to tumors and …

Natural killer T (NKT) cells are important regulatory lymphocytes that have been shown in
mouse studies, to have a crucial role in promoting immunity to tumours, bacteria and viruses …

CD1d-dependent natural killer T (NKT) cells are a unique T-cell subset with the ability to
regulate the immune system in response to a broad range of diseases. That low NKT-cell …

Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …