The broadening of accessible methodologies has enabled mechanistic insights into single-
pathogen infections, yet the molecular mechanisms underlying co-infections remain largely …

Gastrointestinal cell culture technology has evolved in the past decade with the integration
of microfluidic technologies, bringing advantages with greater selectivity and cost …

The anaerobic cultivation of fecal microbiota is a promising approach to investigating how
gut microbial communities respond to specific intestinal conditions and perturbations. Here …

Non-antibiotic drugs can alter the composition of the gut microbiome, with largely undefined
implications for human health. Here we compared the susceptibility of commensal and …

Per-and polyfluoroalkyl Substances (PFAS)–the so-called 'forever chemicals'–are a major
cause of environmental and health concern due to their toxicity and long-term persistence …

Contamination by industrial and agricultural chemicals like pesticides are a cause of great
concern due to the risk to human and environmental health. While these chemicals are often …

Polycyclic polyprenylated acylphloroglucinols (PPAPs) comprise a large group of
compounds of mostly plant origin. The best-known compound is hyperforin from St. John's …

Clostridioides difficile infections often occur after antibiotic use, but they have also been
linked to proton-pump inhibitor (PPI) therapy. The underlying mechanism—whether infection …

The intestinal microbiota is thought to modulate immune responsiveness to vaccines.
Human studies on this topic, however, have yielded inconsistent results. We hypothesized …

The rise in antimicrobial resistance poses a worldwide threat, reducing the efficacy of
common antibiotics. Yet, determining the antimicrobial activity of new chemical compounds …