The aim of this ESC Guideline is to help health professionals manage people with heart
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …

Hypertrophic cardiomyopathy (HCM) was traditionally described as an autosomal dominant
Mendelian disease but is now increasingly recognized as having a complex genetic …

Abstract Document Reviewers: Rudolf A. de Boer (CPG Review Coordinator)(Netherlands),
P. Christian Schulze (CPG Review Coordinator)(Germany), Magdy Abdelhamid (Egypt) …

Hypertrophic cardiomyopathy (HCM) is a common, serious, genetic heart disorder. Rare
pathogenic variants in sarcomere genes cause HCM, but with unexplained phenotypic …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

This document describes the contribution of clinical criteria to the interpretation of genetic
variants using heritable Mendelian cardiomyopathies as an example. The aim is to assist …

Importance Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death
in young people. Although rare genetic variants are well-established contributors to HCM …

Hypertrophic cardiomyopathy (HCM) is an inherited myocardial disease with the presence of
left ventricular hypertrophy (LVH). The disease is characterized by high locus, allelic and …

There is increasing understanding of the genetic basis to dilated cardiomyopathy and in this
review, we offer a practical primer for the practising clinician. We aim to help all clinicians …

Heritable cardiomyopathies are a class of heart diseases caused by variations in a number
of genetic loci. Genetic variants on one allele lead to either a degraded protein, which …