It has been widely known that oxidative stress disrupts the balance between reactive oxygen
species (ROS) and the antioxidant system in the body. During pregnancy, the physiological …

The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

STUDY QUESTION Which add-ons are safe and effective to be used in ART treatment?
SUMMARY ANSWER Forty-two recommendations were formulated on the use of add-ons in …

BACKGROUND Advanced maternal age is associated with decreased oocyte quantity and
quality as well as uterine and placental dysfunctions. These changes lead to infertility …

STUDY QUESTION What is the recommended management for couples presenting with
unexplained infertility (UI), based on the best available evidence in the literature …

The literature on the relationship between diet and human fertility has greatly expanded over
the last decade, resulting in the identification of a few clear patterns. Intake of supplemental …

Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the …

Besides aging, a number of non-modifiable lifestyle-related factors, such as smoking,
elevated consumption of caffeine and alcohol, stress, agonist sports, chronic exposure to …

Infertility is an increasing problem that affects couples attempting pregnancy. A growing
body of evidence points to a link between diet and female fertility. In fact, data show that a …