Adult neurogenesis in the mammalian brain: significant answers and significant questions

G Ming, H Song - Neuron, 2011 - cell.com
Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …

Pattern separation: a common function for new neurons in hippocampus and olfactory bulb

A Sahay, DA Wilson, R Hen - Neuron, 2011 - cell.com
While adult-born neurons in the olfactory bulb (OB) and the dentate gyrus (DG) subregion of
the hippocampus have fundamentally different properties, they may have more in common …

Involvement of adult hippocampal neurogenesis in learning and forgetting

S Yau, A Li, KF So - Neural plasticity, 2015 - Wiley Online Library
Adult hippocampal neurogenesis is a process involving the continuous generation of
newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested …

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology

C Bardy, M Van Den Hurk, B Kakaradov, JA Erwin… - Molecular …, 2016 - nature.com
Human neural progenitors derived from pluripotent stem cells develop into
electrophysiologically active neurons at heterogeneous rates, which can confound disease …

Functional properties of cortical feedback projections to the olfactory bulb

F Markopoulos, D Rokni, DH Gire, VN Murthy - Neuron, 2012 - cell.com
Sensory perception is not a simple feed-forward process, and higher brain areas can
actively modulate information processing in" lower" areas. We used optogenetic methods to …

Activation of adult-born neurons facilitates learning and memory

M Alonso, G Lepousez, S Wagner, C Bardy… - Nature …, 2012 - nature.com
Thousand of local interneurons reach the olfactory bulb of adult rodents every day, but the
functional effect of this process remains elusive. By selectively expressing channelrhodopsin …

Development of the mammalian main olfactory bulb

C Tufo, S Poopalasundaram, A Dorrego-Rivas… - …, 2022 - journals.biologists.com
The mammalian main olfactory bulb is a crucial processing centre for the sense of smell. The
olfactory bulb forms early during development and is functional from birth. However, the …

Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb

A Deshpande, M Bergami, A Ghanem… - Proceedings of the …, 2013 - pnas.org
Identifying the connectome of adult-generated neurons is essential for understanding how
the preexisting circuitry is refined by neurogenesis. Changes in the pattern of connectivity …

[HTML][HTML] Integration of GABAergic interneurons into cortical cell assemblies: lessons from embryos and adults

G Bartolini, G Ciceri, O Marín - Neuron, 2013 - cell.com
In the forebrain, cortical structures consist of networks of excitatory and inhibitory neurons
born in distant locations. Understanding how these two major classes of neurons integrate …

Adult neurogenesis and the future of the rejuvenating brain circuits

G Lepousez, A Nissant, PM Lledo - Neuron, 2015 - cell.com
For a long time, the mammalian brain has been perceived to be a static organ. However, the
discovery of adult neurogenesis in most mammalian species, including humans, monkeys …