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Glycoprotein synthesis: an update
DP Gamblin, EM Scanlan, BG Davis - Chemical reviews, 2009 - ACS Publications
1.1 Aims This review updates our original review on the synthesis of glycoproteins.(1) Its
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …
Synthetic routes to thiooligosaccharides and thioglycopeptides
K Pachamuthu, RR Schmidt - Chemical reviews, 2006 - ACS Publications
The ongoing ability of bacteria to resist current antibiotic treatments highlights the need for
alternative strategies for inhibiting their pathogenicity. For many pathogens, including …
alternative strategies for inhibiting their pathogenicity. For many pathogens, including …
Metal-catalyzed 1, 2-shift of diverse migrating groups in allenyl systems as a new paradigm toward densely functionalized heterocycles
A general, mild, and efficient 1, 2-migration/cycloisomerization methodology toward
multisubstituted 3-thio-, seleno-, halo-, aryl-, and alkyl-furans and pyrroles, as well as fused …
multisubstituted 3-thio-, seleno-, halo-, aryl-, and alkyl-furans and pyrroles, as well as fused …
One-step conversion of unprotected sugars to β-glycosyl azides using 2-chloroimidazolinium salt in aqueous solution
One-step conversion of unprotected sugars to β-glycosyl azides using 2-chloroimidazolinium
salt in aqueous solution - Chemical Communications (RSC Publishing) DOI:10.1039/B905761G …
salt in aqueous solution - Chemical Communications (RSC Publishing) DOI:10.1039/B905761G …
Chemical methods for encoding and decoding of posttranslational modifications
A large array of posttranslational modifications can dramatically change the properties of
proteins and influence different aspects of their biological function such as enzymatic …
proteins and influence different aspects of their biological function such as enzymatic …
An advance in the chemical synthesis of homogeneous N-linked glycopolypeptides by convergent aspartylation
We describe a useful advance in glycopeptide synthesis. We have developed a one-flask
aspartylation/deprotection method, wherein long peptide fragments, bearing proximal …
aspartylation/deprotection method, wherein long peptide fragments, bearing proximal …
Carbohydrate diversity: synthesis of glycoconjugates and complex carbohydrates
A Hölemann, PH Seeberger - Current opinion in biotechnology, 2004 - Elsevier
The fundamental role of glycoconjugates in many biological processes is now well
appreciated and has intensified the development of innovative and improved synthetic …
appreciated and has intensified the development of innovative and improved synthetic …
Stereoselective Construction of β‐Mannopyranosides by Anomeric O‐Alkylation: Synthesis of the Trisaccharide Core of N‐linked Glycans
H Nguyen, D Zhu, X Li, J Zhu - Angewandte Chemie, 2016 - Wiley Online Library
A new and efficient approach for direct and stereoselective synthesis of β‐
mannopyranosides by anomeric O‐alkylation has been developed. This anomeric O …
mannopyranosides by anomeric O‐alkylation has been developed. This anomeric O …
Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction
A Brik, S Ficht, YY Yang, CS Bennett… - Journal of the American …, 2006 - ACS Publications
A novel method for the synthesis of N-linked glycopeptides using the sugar-assisted ligation
strategy from cysteine free peptides is presented. The ligation junction tolerates a variety of …
strategy from cysteine free peptides is presented. The ligation junction tolerates a variety of …
Recent carbohydrate-based chemoselective ligation applications
Chemoselective ligation reactions are highly efficient and specific covalent bond forming
reactions capable of proceeding within a physiological environment. Chemoselective …
reactions capable of proceeding within a physiological environment. Chemoselective …