Plasmodium—a brief introduction to the parasites causing human malaria and their basic biology
S Sato - Journal of physiological anthropology, 2021 - Springer
Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …
clinically and economically as it prevails in poorer countries and regions, strongly hindering …
Drug resistance in Plasmodium
A marked decrease in malaria-related deaths worldwide has been attributed to the
administration of effective antimalarials against Plasmodium falciparum, in particular …
administration of effective antimalarials against Plasmodium falciparum, in particular …
Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical …
RW van der Pluijm, M Imwong, NH Chau… - The Lancet infectious …, 2019 - thelancet.com
Background The emergence and spread of resistance in Plasmodium falciparum malaria to
artemisinin combination therapies in the Greater Mekong subregion poses a major threat to …
artemisinin combination therapies in the Greater Mekong subregion poses a major threat to …
Changing prevalence of potential mediators of aminoquinoline, antifolate, and artemisinin resistance across Uganda
Abstract Background In Uganda, artemether-lumefantrine is recommended for malaria
treatment and sulfadoxine-pyrimethamine for chemoprevention during pregnancy, but drug …
treatment and sulfadoxine-pyrimethamine for chemoprevention during pregnancy, but drug …
Antimalarial drug resistance in Africa: the calm before the storm?
Antimalarial drug resistance, in particular resistance to Plasmodium falciparum, challenges
the treatment and control of malaria. In this Review, we summarise evolving patterns of …
the treatment and control of malaria. In this Review, we summarise evolving patterns of …
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
F Ariey, B Witkowski, C Amaratunga, J Beghain… - Nature, 2014 - nature.com
Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens
malaria control and elimination activities worldwide. To monitor the spread of artemisinin …
malaria control and elimination activities worldwide. To monitor the spread of artemisinin …
Genetic markers associated with dihydroartemisinin–piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype–phenotype association study
Background As the prevalence of artemisinin-resistant Plasmodium falciparum malaria
increases in the Greater Mekong subregion, emerging resistance to partner drugs in …
increases in the Greater Mekong subregion, emerging resistance to partner drugs in …
Artemisinin action and resistance in Plasmodium falciparum
The worldwide use of artemisinin-based combination therapies (ACTs) has contributed in
recent years to a substantial reduction in deaths resulting from Plasmodium falciparum …
recent years to a substantial reduction in deaths resulting from Plasmodium falciparum …
[HTML][HTML] Plasmodium falciparum resistance to artemisinin-based combination therapies
Highlights•Mutant K13-mediated artemisinin resistance involves reduced hemoglobin
endocytosis.•Artemisinin partial resistance has emerged in Africa.•Novel PfCRT mutations …
endocytosis.•Artemisinin partial resistance has emerged in Africa.•Novel PfCRT mutations …
Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa
Malaria, mostly due to Plasmodium falciparum infection in Africa, remains one of the most
important infectious diseases in the world. Standard treatment for uncomplicated P …
important infectious diseases in the world. Standard treatment for uncomplicated P …