Amino acids are the building blocks of protein synthesis. They are structural elements and
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …

Simple Summary Glioblastoma is among the most lethal cancers in humans. Glioblastomas
exhibit a striking heterogeneity, which is maintained by a highly plastic, adaptable …

Ferroptosis is a lipid peroxidation-driven and iron-dependent programmed cell death
involved in multiple physical processes and various diseases. Emerging evidence suggests …

Although oxaliplatin-based chemotherapy has been effective in the treatment of
hepatocellular carcinoma (HCC), primary or acquired resistance to oxaliplatin remains a …

Metabolic reprogramming plays a crucial role in the development of hepatocellular
carcinoma (HCC). However, the key drivers of metabolic reprogramming underlying HCC …

Tumors are comprised of a multitude of cell types spanning different microenvironments.
Mass spectrometry imaging (MSI) has the potential to identify metabolic patterns within the …

The recent torrent of structures of chromatin complexes determined by cryoelectron
microscopy provides an opportunity to discern general principles for how chromatin factors …

The development and immune evasion of cancer stem cells (CSCs) limit the efficacy of
currently available anticancer therapies. Recent studies have shown that epigenetic …

Maturation of eukaryotic pre-mRNAs via splicing and polyadenylation is modulated across
cell types and conditions by a variety of RNA-binding proteins (RBPs). Although there exist …

Drug resistance remains a major challenge in cancer treatment, necessitating the
development of novel strategies to overcome it. Protein arginine methyltransferases …