Stress and adolescence: vulnerability and opportunity during a sensitive window of development
Adolescence is a period of dynamic change across multiple systems. Concurrent maturation
of neural, biological, and psychosocial functioning renders adolescence a time of …
of neural, biological, and psychosocial functioning renders adolescence a time of …
Childhood adversity and neural development: A systematic review
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …
development, although existing evidence for this varies. We present a meta-analysis and …
[HTML][HTML] Early social adversity, altered brain functional connectivity, and mental health
Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …
factors for the onset of severe mental disorders and strong and consistent predictors of …
Social isolation and the brain: effects and mechanisms
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …
reduction in social interaction, which is associated with many adverse effects on health in …
[HTML][HTML] Early life stress and brain function: Activity and connectivity associated with processing emotion and reward
Investigating the developmental sequelae of early life stress has provided researchers the
opportunity to examine adaptive responses to extreme environments. A large body of work …
opportunity to examine adaptive responses to extreme environments. A large body of work …
Early experiences of threat, but not deprivation, are associated with accelerated biological aging in children and adolescents
Background Recent conceptual models argue that early life adversity (ELA) accelerates
development, which may contribute to poor mental and physical health outcomes. Evidence …
development, which may contribute to poor mental and physical health outcomes. Evidence …
Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential
The immediate and long-term effects of exposure to early life stress (ELS) have been
documented in humans and animal models. Even relatively brief periods of stress during the …
documented in humans and animal models. Even relatively brief periods of stress during the …
Early adversity and development: parsing heterogeneity and identifying pathways of risk and resilience
DG Gee - American Journal of Psychiatry, 2021 - psychiatryonline.org
Adversity early in life is common and is a major risk factor for the onset of psychopathology.
Delineating the neurodevelopmental pathways by which early adversity affects mental …
Delineating the neurodevelopmental pathways by which early adversity affects mental …
Early deprivation alters structural brain development from middle childhood to adolescence
Hypotheses concerning the biologic embedding of early adversity via developmental
neuroplasticity mechanisms have been proposed on the basis of experimental studies in …
neuroplasticity mechanisms have been proposed on the basis of experimental studies in …