Agrobacterium-Mediated Plant Transformation: the Biology behind the “Gene-Jockeying” Tool

SB Gelvin - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
Agrobacterium tumefaciens and related Agrobacterium species have been known as plant
pathogens since the beginning of the 20th century. However, only in the past two decades …

Epigenetics: regulation through repression

AP Wolffe, MA Matzke - science, 1999 - science.org
Epigenetics is the study of heritable changes in gene expression that occur without a
change in DNA sequence. Epigenetic phenomena have major economic and medical …

A species of small antisense RNA in posttranscriptional gene silencing in plants

AJ Hamilton, DC Baulcombe - Science, 1999 - science.org
Posttranscriptional gene silencing (PTGS) is a nucleotide sequence–specific defense
mechanism that can target both cellular and viral mRNAs. Here, three types of transgene …

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

H Tabara, M Sarkissian, WG Kelly, J Fleenor, A Grishok… - Cell, 1999 - cell.com
Double-stranded (ds) RNA can induce sequence-specific inhibition of gene function in
several organisms. However, both the mechanism and the physiological role of the …

Applications and advantages of virus‐induced gene silencing for gene function studies in plants

TM Burch‐Smith, JC Anderson, GB Martin… - The Plant …, 2004 - Wiley Online Library
Virus‐induced gene silencing (VIGS) is a recently developed gene transcript suppression
technique for characterizing the function of plant genes. The approach involves cloning a …

Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance

P Mourrain, C Béclin, T Elmayan, F Feuerbach… - Cell, 2000 - cell.com
Posttranscriptional gene silencing (PTGS) in plants results from the degradation of mRNAs
and shows phenomenological similarities with quelling in fungi and RNAi in animals. Here …

Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants

O Voinnet, YM Pinto… - Proceedings of the …, 1999 - National Acad Sciences
In transgenic and nontransgenic plants, viruses are both initiators and targets of a defense
mechanism that is similar to posttranscriptional gene silencing (PTGS). Recently, it was …

Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense

X Zhang, YR Yuan, Y Pei, SS Lin, T Tuschl… - Genes & …, 2006 - genesdev.cshlp.org
RNA silencing refers to small regulatory RNA-mediated processes that repress endogenous
gene expression and defend hosts from offending viruses. As an anti-host defense …

RNA-triggered gene silencing

A Fire - Trends in Genetics, 1999 - cell.com
Double-stranded RNA (dsRNA) has recently been shown to trigger sequence-specific gene
silencing in a wide variety of organisms, including nematodes, plants, trypanosomes, fruit …

Nitrate uptake and reduction in higher and lower plants

R Tischner - Plant, Cell & Environment, 2000 - Wiley Online Library
The nitrogen compounds nitrate and ammonium are the minerals that plants need in large
quantities and which limit their growth in temperate zones. The nitrate assimilation pathway …