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Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
Formulation strategies to improve the bioavailability of poorly absorbed drugs with special emphasis on self‐emulsifying systems
Poorly water‐soluble drug candidates are becoming more prevalent. It has been estimated
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …
Lipid based nanocarriers: a translational perspective
Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …
noteworthy achievements in the field of medications as well as drug delivery. The rise of …
Chitosan coated clove oil-based nanoemulsion: An attractive option for oral delivery of leflunomide in rheumatoid arthritis
Rheumatoid arthritis (RA), a distressing inflammatory autoimmune disease, is managed
mainly by Disease-modifying antirheumatic drugs (DMARDs), eg leflunomide (LEF). LEF …
mainly by Disease-modifying antirheumatic drugs (DMARDs), eg leflunomide (LEF). LEF …
Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: design, characterization, in vitro and in vivo …
Naringenin (NRG), predominant flavanone in grapefruits, possesses anti-inflammatory, anti-
carcinogenic, hepato-protective and anti-lipid peroxidation effects. Slow dissolution after oral …
carcinogenic, hepato-protective and anti-lipid peroxidation effects. Slow dissolution after oral …
Self nanoemulsifying drug delivery system (SNEDDS) of rosuvastatin calcium: design, formulation, bioavailability and pharmacokinetic evaluation
The aim of the present study is to improve solubility and bioavailability of Rosuvastatin
calcium using self nanoemulsifying drug delivery system (SNEDDS). Self emulsifying …
calcium using self nanoemulsifying drug delivery system (SNEDDS). Self emulsifying …
Freeze-drying: A flourishing strategy to fabricate stable pharmaceutical and biological products
Freeze-drying (FD) of nanoparticles, microorganisms, genes, and vaccines is an auspicious
technique used to enhance long-term stability and facilitate transportation mainly for …
technique used to enhance long-term stability and facilitate transportation mainly for …
Self-nanoemulsifying drug delivery system (SNEDDS) for improved oral bioavailability of chlorpromazine: in vitro and in vivo evaluation
Background and Objectives: Lipid-based self-nanoemulsifying drug delivery systems
(SNEDDS) have resurged the eminence of nanoemulsions by modest adjustments and offer …
(SNEDDS) have resurged the eminence of nanoemulsions by modest adjustments and offer …
Freeze-drying of emulsified systems: A review
AR do Vale Morais, É do Nascimento Alencar… - International journal of …, 2016 - Elsevier
Colloidal systems such as emulsions, microemulsions and nanoemulsions are able to
transport active molecules, enhance their solubility and stability and minimize their side …
transport active molecules, enhance their solubility and stability and minimize their side …
Systematic approach for the formulation and optimization of solid lipid nanoparticles of efavirenz by high pressure homogenization using design of experiments for …
The nonnucleoside reverse transcriptase inhibitors, used for the treatment of HIV infections,
are reported to have low bioavailability pertaining to high first‐pass metabolism, high protein …
are reported to have low bioavailability pertaining to high first‐pass metabolism, high protein …