In this article, we review clinical research using the mismatch negativity (MMN), a change-
detection response of the brain elicited even in the absence of attention or behavioural task …

Functional decline of physiological systems during ageing leads to age-related diseases.
Dietary glycine increases healthy lifespan in model organisms and might decrease …

Activating Nrf2 by small molecules is a promising strategy to treat postmenopausal
osteoporosis. However, there is currently no Nrf2 activator approved for treating chronic …

Background: Based on the glutamatergic NMDA receptor hypofunction theory of
schizophrenia, NMDA receptor modulators (NMDARMs) may have therapeutic potential in …

Since the early 1990s, the auditory change-detection response, mismatch negativity (MMN)
and its magnetoencephalographic (MEG) equivalent MMNm have been applied in a large …

Glycine is the smallest non-essential, neutral and metabolically inert amino acid, with a
carbon atom bound to two hydrogen atoms, and to an amino and a carboxyl group. This …

Rationale Caffeine exerts positive effects on cognitive and behavioral processes, especially
in sub-optimal conditions when arousal is low. Apart from caffeine, coffee contains other …

This review surveys human event-related brain potential (ERP) and event-related magnetic
field (ERF) approaches to psychopharmacology and psychopathology, and the way in which …

Glycine increases N-methyl-d-aspartate receptor (NMDAR) mediated glutamatergic function.
Mismatch negativity (MMN) is a proposed biomarker of glutamate-induced improvements in …

OBJECTIVES: Based on the hypothesis of NMDA receptor hypofunction in schizophrenia,
plasma glycine, l-serine, and d-serine levels have been studied, since they could serve as …