Structural inspection for novel Pd (II), VO (II), Zn (II) and Cr (III)-azomethine metal chelates: DNA interaction, biological screening and theoretical treatments

FS Aljohani, AM Abu-Dief, RM El-Khatib… - Journal of Molecular …, 2021 - Elsevier
An alternative sequence of bioactive series, using novel Schiff base derivative (1-Quinolin-8-
yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar …

Oxicams as Bioactive Ligand System in Coordination Complexes and Their Biological Applications

M Naeem, A Ashraf, M Imran, WA Siddiqui… - Comments on …, 2024 - Taylor & Francis
Oxicam is a class of non-steroidal anti-inflammatory drugs (NSAIDs) that exhibits structural
similarities to the enolic acid of 4-hydroxy-1, 2-benzothiazine carboxamides. The oxicam …

Optimization for synthesized quinoline-based Cr3+, VO2+, Zn2+ and Pd2+ complexes: DNA interaction, biological assay and in-silico treatments for verification

HA Al-Abdulkarim, RM El-khatib, FS Aljohani… - Journal of Molecular …, 2021 - Elsevier
A novel momonuclear metal chelates were derived from Zn (II), Pd (II), VO (II) and Cr (III) ions
with azomethine (BSQ)[BSQ= 4-Bromo-2-(quinolin-8-yliminomethyl)-phenol] ligand. The …

Synthesis and structural elucidation for new pyrano thiazole complexes: Biological screening and effects on DNA through in-vitro and in-silico approaches

SO Alzahrani, AM Abu-Dief, K Alkhamis… - Journal of Molecular …, 2021 - Elsevier
Novel bioactive complexes were prepared from Cu (II), Fe (III) and Pd (II) ions with pyrano
thiazole derivative (PTP)[2-amino-6-oxo-3-(piperidinylamidino)-4-phenyl-6, 7-dihydro …

Exploring the antimicrobial, antioxidant and cytotoxic activities of organyltellurium (IV) complexes incorporating 2‐hydroxy‐1‐naphthaldehyde schiff base ligand …

M Dalal, J Devi, N Antil, B Kumar… - Applied …, 2024 - Wiley Online Library
In this study, Schiff base ligand 1, 1′‐((propane‐1, 3‐diylbis azaneylylidene) bis
(methaneylylidene)) bis (naphthalen‐2‐ol) based Organyltellurium (IV) complexes were …

Synthesis and characterization for pharmaceutical models from Co (II), Ni (II) and Cu (II)-thiophene complexes; apoptosis, various theoretical studies and …

HM Abumelha, F Alkhatib, S Alzahrani… - Journal of Molecular …, 2021 - Elsevier
Abstract New Co (II), Ni (II) and Cu (II) complexes were prepared from thiophene derivative
and then characterized to elucidate their chemical formulae. IR-spectral data suggested a …

[HTML][HTML] Synthesis, anticancer activity, and molecular docking of new pyrazolo [1, 5-a] pyrimidine derivatives

A Hossan, AF Alrefaei, HA Katouah, A Bayazeed… - Journal of Saudi …, 2023 - Elsevier
The reaction of 3-aminopyrzoles with dimethylamino-acrylonitrile derivatives was utilized for
the production of new functionalized pyrazolopyrimidine compounds 4a-c and 6a-c. The …

[PDF][PDF] Synthesis and characterization of Cu (II)-pyrazole complexes for possible anticancer agents; conformational studies as well as compatible in-silico and in-vitro …

E Aljuhani, MM Aljohani, A Alsoliemy, R Shah… - Heliyon, 2021 - cell.com
New pyrazole derivatives were prepared and used to synthesize new bioactive agents from
Cu (II) complexes that have OSN donors. Analytical and spectral (IR, UV-Vis, MS, 1 H NMR …

New Cu (II) and VO (II)-O, N, O-aroylhydrazone complexes: biological evaluation, catalytic performance, ctDNA interaction, DFT, pharmacophore, and docking …

MSS Adam, S Shaaban, ME Khalifa, M Alhasani… - Journal of Molecular …, 2021 - Elsevier
Abstract Polar mononuclear Cu (II)(CuSSL· H 2 O) and VO (II)(VOSSL· 0.5 H 2 O) complexes
were prepared employing 4-hydroxy-3-((2-(4-methoxybenzoyl) hydrazineylidene) methyl) …

Theoretical investigation by DFT and molecular docking of synthesized oxidovanadium (IV)-based imidazole drug complexes as promising anticancer agents

AS Basaleh, FY Alomari, AA Sharfalddin, NS Al-Radadi… - Molecules, 2022 - mdpi.com
Vanadium compounds have been set in various fields as anticancer, anti-diabetic, anti-
parasitic, anti-viral, and anti-bacterial agents. This study reports the synthesis and structural …